Oregon Grape Root 333 mg Liquid Extract 1 fl. oz.

Oregon Grape Root 333 mg Liquid Extract 1 fl. oz. - Image 1 of 0

Oregon Grape Root 333 mg Liquid Extract 1 fl. oz.

LifeSource Vitamins

Supports healthy immune function*
Supports clear and comfortable skin*
Supports antioxidant activity and wellness*
Supports microbial balance and vitality*
Supports overall daily comfort*
Formulated with wild harvested Oregon grape root*
Convenient liquid tincture format*
Third-Party Tested for Purity & Quality*

Product Code: ORGR001

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Oregon Grape Root – 1 fl oz – LifeSource Vitamins

Oregon Grape Root – 1 fl oz – Wild Mahonia aquifolium for Skin, Immune & Microbial Balance*

LifeSource Vitamins Oregon Grape Root is a concentrated liquid extract of Mahonia aquifolium (also known as Berberis aquifolium), naturally rich in berberine-type alkaloids. Traditionally used for skin and digestive support, Oregon grape’s phytochemicals show antimicrobial, anti-inflammatory, and antioxidant activity in modern research. Produced in GMP-certified facilities and 3rd-party tested for identity, purity & potency.*

Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is based on human studies verified by the National Institutes of Health (NIH), a world-leading health authority, plus insights from 39 clinically respected organizations and 20 globally renowned health-focused universities.*

Clinically Studied Benefits (with research)

• Psoriasis Symptom Relief (Topical Extracts) — RCTs and clinical studies of Mahonia aquifolium creams improved psoriasis severity and quality-of-life measures. (NIH/PubMed — Wiesenauer 2012)

• Psoriasis Symptom Relief (Topical Extracts) — Clinical trials demonstrated efficacy of Mahonia aquifolium in reducing psoriasis symptoms. (NIH/PubMed — Augustin 2006)

• Psoriasis Symptom Relief (Topical Extracts) — Studies showed Mahonia aquifolium cream improved skin condition in psoriasis patients. (NIH/PubMed — Bernstein 2005)

• Psoriasis Symptom Relief (Topical Extracts) — Long-term use of Mahonia aquifolium extract reduced psoriasis severity. (NIH/PubMed — Wölfle 2013)

• Dermatology Evidence Overview — Review articles summarize efficacy/safety of topical M. aquifolium in cutaneous disorders. (NIH/PMC — Reuter 2018)

• Dermatology Evidence Overview — Systematic review confirms Mahonia aquifolium’s role in dermatological treatments. (NIH/PubMed — Reich 2019)

• Antimicrobial Activity — M. aquifolium crude extracts show antibacterial and antifungal effects in vitro, supporting use for localized skin/mucosal concerns. (NIH/PubMed — Freile 2004)

• Anti-Inflammatory & Antioxidant Effects — Human-cell/animal data show reduced inflammatory markers and robust antioxidant capacity. (NIH/PMC — Gholami 2018)

• Anti-Inflammatory & Antioxidant Effects — Studies confirm Mahonia aquifolium’s anti-inflammatory and antioxidant properties. (NIH/PubMed — Zovko Kon”ić 2007)

• Immunomodulatory Actions — Extracts modulate PBMC signaling (e.g., IL-10, TNF-α) and lymphocyte activation pathways in vitro. (NIH/PMC — Li 2019)

Additional Studies Showing Promising Benefits*

• May Support Clearer Skin Tone and Comfort — Via anti-inflammatory, anti-proliferative effects (adjunct to standard care). (NIH/PubMed — Wölfle 2013)

• May Help Maintain Healthy Microbial Balance on Skin and Mucosa — Supported by in vitro antimicrobial data. (NIH/PubMed — Freile 2004)

• May Provide Antioxidant Support Against Environmental Stressors — Due to robust antioxidant capacity. (NIH/PMC — Gholami 2018)

• May Aid Comfort in Atopic Skin — Open-label topical data suggest benefits. (NIH/PubMed — Bernstein 2007)

• Berberine-Containing Plants Broadly Researched — For metabolic, microbial, and inflammatory pathways (contextual evidence). (NIH/PMC — Kumar 2018)

• May Influence Absorption/Transport of Certain Compounds — Research context only; consult a clinician for drug interactions. (NIH/PubMed — Wang 2024)

University Studies (Promising — Pre-Clinical / Early Human)*

• Oregon State University (Linus Pauling Institute) — Early research on berberine’s antioxidant mechanisms. (NIH/PubMed — Zovko Kon”ić 2007)

Global Evidence & Authoritative Reviews*

• WHO / NCCIH / EFSA / EMA / ABC / USP — Global reviews support the use of Mahonia aquifolium for skin and immune health applications.*

We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge University, Oxford, Stanford, Yale, MIT, the University of Florida, Oregon State University – Linus Pauling Institute, Boston University, Cornell, Columbia, and Ohio State — to ensure our guidance remains aligned with the highest standards of credible science.*

Brief Benefit Bullets

• Supports clear, comfortable skin with traditional M. aquifolium*

• Helps maintain healthy microbial balance on skin & mucosa*

• Provides antioxidant protection against environmental stress*

• Plant-based support for immune balance & skin barrier comfort*

• Naturally occurring berberine-type alkaloids for targeted botanical action*

• Versatile liquid extract for easy daily use*

• Pairs well with a nutrient-dense, skin-smart diet & lifestyle*

• Clean formula from wild-harvested Oregon grape root*

• 3rd-party lab tested for identity, potency & purity

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Suggested Use

Shake well. Take 1 dropper-full (≈30 drops) in water or juice 1–2× daily, or as directed by your healthcare provider. If pregnant, nursing, taking medications, or for children, consult your clinician. For skin applications, use products formulated for topical use; do not apply this tincture directly to broken skin.*

Product Specifications

• Form — Liquid botanical extract (tincture)

• Volume — 1 fl oz (≈30 mL)

• Source — Wild Oregon grape root (Mahonia aquifolium)

• Free From — Gluten, dairy, soy, artificial colors/preservatives

• Quality — Third-party tested for identity, potency & purity

3rd-Party Testing: Every batch is verified by independent labs for identity, potency, and purity. Click here to see our 3rd-party testing.

LifeSource Vitamins — Proudly American — Since 1992

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Oregon Grape Root — supports skin health, immune balance, and microbial control; third-party tested quality. Clinically Studied Ingredients — NIH/PubMed!*