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Goldenseal 500 mg - 100 Capsules

LifeSource Vitamins

1 Reviews

Convenient 500 mg standardized capsules*
Contains natural berberine and hydrastine alkaloids*
Supports immune function during acute health challenges*
Promotes respiratory health and mucosal tissue integrity*
Easy-to-swallow capsules with no bitter taste*
Precise dosing; 100 capsules for extended use*
3rd-party lab tested for purity & potency

Product Code: GOLD002

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Goldenseal Root — LifeSource Vitamins

Goldenseal Root — 100 Capsules — 500 mg — Convenient Immune & Respiratory Support*

LifeSource Vitamins Goldenseal Root provides Hydrastis canadensis root, naturally containing the isoquinoline alkaloids berberine and hydrastine. Goldenseal has a long history of traditional use; modern human research on its key constituents explores support for immune, respiratory, and mucosal wellness. Produced in FDA-registered, GMP-certified facilities and supported by NIH-indexed human clinical studies. Our approach focuses on efficacy, safety, and transparency — ensuring every ingredient meets LifeSource’s uncompromising standards for quality and science.*

Research Promise. Every benefit listed is backed by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (PMC) when available. We also reference reviews from 39 leading health organizations and insights from 20 top global universities to keep guidance aligned with credible science.*

Clinically Studied Benefits

Supports digestive comfort* — Systematic reviews of clinical trials report berberine-containing preparations improved diarrhea outcomes vs controls (heterogeneity noted). (NIH/PubMed — Wang, 2020; NIH/PMC — Chu, 2020)
Supports IBS-D symptom relief* — Randomized clinical trial: berberine HCl reduced IBS-D symptoms and improved quality of life vs placebo. (NIH/PubMed — Chen, 2015)
Characterized human exposure* — Hydrastine pharmacokinetics described after oral goldenseal in healthy adults. (NIH/PubMed — Gurley, 2015)
Use with medication awareness* — Human/ex vivo data indicate goldenseal/berberine can inhibit CYP3A4/2D6/2C9; consult your physician if using medications. (NIH/PubMed — Foster, 2003; NIH/PMC — Henderson, 2011)
Contemporary overview* — Narrative review summarizes chemistry, bioactivity, and evidence gaps for goldenseal. (NIH/PubMed — Kaskoos, 2020)

Additional / Promising Evidence

May support respiratory/mucosal wellness* — Mechanistic data (efflux-pump inhibition and synergy) provide rationale; more human trials needed. (NIH/PMC — Ettefagh, 2011)
May influence gut microbiome* — Emerging evidence links berberine to microbiota shifts; clinical relevance varies. (NIH/PubMed — Zhang, 2019)
Identity and quality support* — Analytical studies define typical hydrastine/berberine ranges in authentic goldenseal. (NIH/PMC — Applequist, 2008; NIH/PubMed — Brown, 2003)

University / Academic Context

Harvard: Summarizes human research on herbal constituents (incl. berberine) for digestive comfort and general wellness. (NIH/PubMed — Anh, 2020)
Linus Pauling Institute (OSU): Discusses evidence and safety considerations for botanicals affecting mucosal integrity.
Mayo Clinic: Educational reviews note traditional use; emphasize quality and medication-interaction awareness.

Global Evidence & Authoritative Reviews

Cochrane: Reviews herbal/adjunct approaches across respiratory and digestive topics; evidence ranges from limited to moderate depending on endpoint. (NIH/PubMed — Mott, 2020)
American Botanical Council (ABC): Monographs emphasize identity testing and authentic alkaloid profiles for quality assurance.

We monitor research from leading institutions — Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, the University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, and Ohio State — to keep our guidance aligned with credible science.*

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Key Ingredients

Goldenseal Root (Hydrastis canadensis) — 500 mg per capsule: Natural source of hydrastine and berberine; identity and quality are supported by analytical profiling of authentic goldenseal.* (NIH/PMC — Applequist, 2008; NIH/PubMed — Brown, 2003)

Brief Benefit Bullets

Supports immune and respiratory wellness*
Promotes healthy mucosal tissue integrity*
Supports digestive comfort*
Convenient capsules for easy daily use*
3rd-party lab tested for purity & potency

Suggested Use

Take as directed on the product label, or as advised by a healthcare professional. If pregnant, nursing, taking medications (e.g., those metabolized by CYP3A4/2D6/2C9), or have a medical condition, consult your physician. Do not exceed recommended use. Keep out of reach of children.*

Product Specifications

Serving Size — 1 Capsule
Servings Per Container — 100
Form — Vegetarian Capsules
Free From — Non-GMO; no artificial colors or preservatives*
Quality — Third-party tested for identity, potency & purity

3rd Party Testing: Every LifeSource Vitamins product is tested by independent labs to verify identity, purity, potency, and label accuracy. Click Here To View Our 3rd-Party Testing Process

LifeSource Vitamins — Proudly American — Since 1992

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before taking any supplements.*

LifeSource Vitamins Goldenseal Root — 500 mg (100 capsules) supports immune, respiratory & mucosal wellness. Non-GMO, 3rd-party tested. Clinically Studied Ingredients — NIH/PubMed!*