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E-400 - Mixed Tocopherols- 100 Softgels
E-400 - Mixed Tocopherols- 100 Softgels

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E- 400
Mixed Tocopherols

100 Softgels


Also Available in 200 Count Value Size

Possible Benefits of Vitamin E:

  • Prevents the clogging of arteries that contributes to heart disease*
  • Oxidative Stress and Free Radical Support
  • May reduce the risk of death from stroke in postmenopausal women*
  • May reduce the risk of stroke in people undergoing treatment for atherosclerosis*
  • Inhibits the growth of cancer cells in cancers associated with hormonal causes (i.e., prostate cancer, breast cancer)*
  • Reduces sensitivity to the sun in photodermatitis*
  • May prevent osteoarthritis, and is useful for pain relief and treatment of inflamed joints*
  • Improves cognitive performance in patients with Alzheimer’s disease, and in conjunction with Vitamin C, may prevent the development of Alzheimer’s disease*
  • Helps prevent the long term consequences of menopause, and is the best option to reduce hot flashes in menopausal women*
  • Protects against cataracts and age-related macular degeneration*
  • Helps control blood sugar and cholesterol levels in people with type 2 diabetes, and may help prevent damage to the eyes and nerves associated with diabetes*
  • Slows the effects of aging*
  • Improves the speed of healing wounds*
  • Lowers blood pressure*
  • Reduces scarring from wounds and injuries*
  • Slows progression of Parkinson’s disease*
  • Helpful in treating lupus*
  • Avoiding miscarriage in cases where vitamin E deficiency is a promoting factor*

Read Below: Full Description, Clinical Studies & Research on Vitamin E.

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Description Supplement Facts

Also Available in 200 Count Value Size

Vitamin E is the term used for eight naturally occurring, fat-soluble nutrients called tocopherols. Alpha-Tocopherol is essential, has the highest biological activity, and predominates in many species.

Symptoms of Vitamin E Deficiency:

The symptoms of vitamin E deficiency include muscle weakness, loss of muscle mass, abnormal eye movements, impaired vision, and unsteady gait. In more severe cases, vitamin E deficiency can compromise the function of the liver and kidneys. Vitamin E deficiency has been associated with serial miscarriages and premature delivery in pregnant women.

In human beings, vitamin E is the most important fat-soluble antioxidant. It prevents the potentially harmful oxidation of fat compounds and enhances the functioning of vitamin A. It is an anti-pollutant for the lungs. It helps the healing of scar tissue when taken internally and also when applied externally.

The best natural sources are wheat germ, whole grains, vegetable oils, soya beans, nuts, apples, apricots and green vegetables.

Vitamin E deficiency may cause anemia, as a result of red blood cell destruction and neurological dysfunction, myopathies, and diminished erythrocyte life span. New clinical evidence from heavy drinkers suggests that alcohol may increase the oxidation of Alpha-Tocopherol. Increased demand has also been observed in premature infants and patients with malabsorption.

Your best bet for a good blend of mixed tocopherols in a softgel form is LifeSource Vitamins Vitamin E with 20% Mixed Tocopherols.

See Other LifeSource Vitamins Vitamin E Products, Articles, and Studies: Click Here

Current Research on Vitamin E:

Photo-protective Effects:
Tocopherol may play an essential role in the defense of eye and skin cells against many light-induced diseases and/or conditions. Vitamin E may share a protective role in the membranes of plant and animal cells that are naturally predisposed to photo-oxidative stress. It may play a prophylactic role against diseases and conditions of the eye (cataractogenesis and retinal photodeterioration) and skin (erythrocyte photochemolysis, photoerythema, photoaging, and photocarcinogenesis).

UV radiation can cause adverse effects such as sunburn, immunologic suppression, photo-aging, skin tumors, and photosensitivity reactions. In a study looking at the protective effects of vitamin C and vitamin E against sunburn, researchers found combined vitamins C and E reduced sunburn reaction. It was concluded that this might help reduce the risk for later UV-induced skin damage.

Crohn's Disease and Short Bowel Syndrome: Vitamin E deficiency can result from malabsorption of the vitamin due to fat malabsorption resulting from Crohn's disease with short-bowel syndrome.

A study reported in the American Journal of Clinical Nutrition showed that vitamin E preparations may aid in intestinal absorption of vitamin E in short-bowel syndrome. The study also showed that vitamin E supplementation may help stem and allow for a partial reversal of the neurologic complications seen with vitamin E deficiency.

Heart Disease: Vitamin E may play a crucial role in the pathogenesis of atherosclerosis. The hypothesis is that vitamin E helps protect against the oxidation of unsaturated lipids in the low-density lipoprotein (LDL) particle that initiates a complex sequence of events leading to atherosclerotic plaque.

Increased dietary vitamin E concentrations may be associated with a lower risk of stroke. In a study done in 2000, vitamin E supplementation decreased the risk of cerebral infarction, without elevating the risk of subarachnoid hemorrhage. The authors concluded that vitamin E supplementation may help prevent ischemic stroke in high-risk hypertensive patients, although further studies are needed.

Alzheimer's Disease and Dementia:
There is increased oxidative damage in the brain of Alzheimer's disease (AD) patients and excess of free radicals. Vitamin E can prevent free-radical-mediated cell death and possibly diminish cognitive deterioration. The results of a clinical trial in 2000 showed that treatment with vitamin E delayed the time to important functional endpoints. It suggested that vitamin E may slow the disease progression in moderately advanced AD patients.

The use of vitamin C and E supplements may protect against the development of dementia and poor cognitive functioning. Results from a study on dementia in elderly men suggested that vitamins E and C might protect against vascular dementia and possibly enhance cognitive function later in life.

Individuals with low vitamin E concentrations may be at greater risk for insulin-dependent diabetes mellitus (IDDM). In 1999, a study published in the Journal of Internal Medicine found an inverse association between serum a-tocopherol concentration and the occurrence of IDDM. Therefore, vitamin E may provide protection against IDDM, which supports the hypothesis that antioxidants may play a crucial role in the pathogenesis of IDDM.

Type 2 diabetes is associated with increased oxidative stress, which is related to an imbalance in the cardiac autonomic nervous system. Antioxidants, such as vitamin E may have beneficial effects on the cardiac autonomic nervous system. A study on patients diagnosed with type 2 diabetes and cardiac autonomic neuropathy showed that 600-mg/d vitamin E administration for 4 months was associated with decreased plasma concentrations of glycated hemoglobin, insulin, norepinephrine, and epinephrine. Vitamin E also improved indexes of oxidative stress. Researchers concluded that chronic vitamin E administration improved the ratio of cardiac sympathetic to parasympathetic tone in patients with type 2 diabetes.

Immune System:
Vitamin E acts as an antioxidant and can assist in the modulation of the immune system. A study investigated the immunologic and antioxidant effects of vitamin E supplementation in healthy Chinese men and women. The data showed elevated plasma vitamin E concentrations and depression in plasma malondialdehyde and urinary DNA adduct 8-hydroxy-2'-deoxyguanosine. The oxidative stress of T-lymphocyte is lowered significantly by vitamin E supplementation. Since it is known that high levels of oxidative stress such as H2O2 inhibited T-cell proliferation, this suggests that vitamin E has an important role in immune function.

Epidemiological studies show a protective role of vitamins as antioxidants in the prevention of age-related cataracts and macular degeneration. In a review of 11 studies, 8 studies found vitamin E was inversely correlated with cataract risk. Based on the observations, researchers concluded that a diet high in vitamins C, E, and carotenoids, may aid in decreasing the development of cataracts and age-related macular degeneration.

Nonalcoholic Steatohepatitis in Children
: A study was done looking at the effects of vitamin E in lowering serum aminotransferase and alkaline phosphatase concentrations in children with nonalcoholic steatohepatitis (NASH) that is associated with obesity. The a-tocopherol concentrations increased significantly with vitamin E supplementation and the serum aminotransferase and alkaline phosphatase concentrations normalized. Researchers concluded that children with NASH should be encouraged to be involved in a weight loss regimen and consider taking supplemental a-tocopherol.

Natural-vs.-Synthetic Vitamin E:
Natural and synthetic forms of a-tocopherol have been shown to be absorbed equally well. A study giving subjects various doses of natural and synthetic vitamin E showed significantly less oxidation of low-density lipoprotein cholesterol (LDL-C) in the subjects given either form of 400 or 800 IU of vitamin E. Researchers concluded that both natural and synthetic forms of vitamin E are as effective inhibiting the oxidation of LDL-C in humans. However natural is always the best way to get absorption into your bloodstream.

LifeSource Vitamins - Vitamin E 400 IU, 100 softgels, most important fat-soluble antioxidant prevents the potentially harmful oxidation of fat compounds, enhances the functioning of vitamin A, helps the healing of scar tissue.

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*Disclaimer: None of the above statements have been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. As always, consult your physician before taking any and all supplements. LifeSource Vitamins. Individual results may vary.

Disclaimer: All the information contained throughout this website is based upon the opinions of the founder of LifeSource Vitamins, Bruce Brightman, and the entire team at LifeSource Vitamins whose relentless research and studies have been ongoing since 1992. Other articles and information are based on the opinions of the authors, who retain the copyright as marked in the article. The information on this site is not intended to replace your health care professional, but to enhance your relationship with them. Doing your own studying and research and taking your health care into your own hands is always best, especially in partnership with your health care professional.

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