Perhaps the biggest appeal of St. John's Wort is the fact that it's so
widely available. It's safe, very effective (for most people), and you
don't need to see a doctor to get it. Well, unless you live in Germany
where it's sold by prescription only. High-quality St. John's Wort can
be as effective as a prescription antidepressant, and this has been
proven by several scientific studies. LifeSource Vitamins is proud to
introduce our clean and pure St. John's Wort. You will love the purity.
What does St. John's Wort may help with:
even in the most modest sense, can keep us from functioning at our best.
St. John's Wort, a perennial extract that blooms from June to September has
been shown to help balance mood, encourage feelings of calmness, and even
support healthy sleeping patterns. Hypericin, one of the active pigments in
St. John's Wort has the ability to naturally support our brain’s serotonin
production. As a result, it may be beneficial in providing the balance
needed to maintain a positive mood naturally without side effects.*
Parts used and where grown:
St. John's Wort is found in Europe and the United States; it is especially
abundant in northern California and southern Oregon. The above-ground
(aerial) parts of the plant are gathered during the flowering season.
Similar species are found around the world.
Historical or traditional use (may or may not be supported by scientific
studies): In ancient Greece, the herb was used to treat many ailments,
including sciatica and poisonous reptile bites. In Europe, St. John's Wort
was, and continues to be, very popular for the topical treatment of wounds
and burns. It is also a folk remedy for kidney and lung ailments as well as
See All LifeSource St. John’s Wort Products, Articles, and Studies:
Active constituents: St. John's wort has a complex diverse chemical makeup
that includes hypericin and other dianthrones, flavonoids, xanthones, and
1. While it was previously thought that the antidepressant actions of St.
John’s wort were due to hypericin and inhibition of the enzyme monoamine
2. Current research has challenged this belief. Recent studies have focused
on other constituents, such as hyperforin, xanthones, and flavonoids.
3 & 4. New research suggests that St. John’s wort extracts exert their
antidepressant actions by inhibiting the reuptake of the neurotransmitters
serotonin, norepinephrine, and dopamine.
5. This action is possibly due to the constituent hyperforin.
6. By making more of these neurotransmitters available to the brain, St.
John’s wort is able to act as an antidepressant.
What the Science Says About St. John’s Wort for Depression
Study results on the effectiveness of St. John’s wort for depression are
A 2009 systematic review of 29 international studies suggested
that St. John’s Wort may be better than a placebo (an inactive
substance that appears identical to the study substance) and as
effective as standard prescription antidepressants for major depression
of mild to moderate severity. St. John’s Wort also appeared to have
fewer side effects than standard antidepressants. The studies—conducted
in German-speaking countries where St. John’s Wort has a long history
of use by medical professionals—reported more positive results than
those done in other countries, including the United States.
Preliminary studies suggest that St. John’s Wort may prevent nerve
cells in the brain from reabsorbing certain chemical messengers,
including dopamine and serotonin. Scientists have found that these
naturally occurring chemicals are involved in regulating mood, but they
are unsure exactly how they work.
University of Maryland Study:
St. John's wort (Hypericum perforatum) has a history of being used
as a medicine dating back to ancient Greece, where it was used for a range
of illnesses, including various "nervous disorders." St. John's wort also
has antibacterial and antiviral properties. Because of its
anti-inflammatory properties, it has been applied to the skin to help heal
wounds and burns. St. John's wort is one of the most commonly purchased
herbal products in the United States.*
In recent years, St. John's wort has been studied extensively as a
treatment for depression. Most studies show that St. John's wort may help
treat mild-to-moderate depression, and has fewer side effects than most
other prescription antidepressants. But it interacts with a number of
medications, so it should be taken only under the guidance of a health care
You shouldn’t try to treat severe depression -- where you may not be able
to function day to day, or have thoughts of harming yourself or others --
with herbs. Always see a doctor if your depression is making it hard for
you to function (See "Precautions" section).
There is good evidence that St. John's wort may reduce symptoms in people
with mild-to-moderate but not severe (or major) depression. In many
studies, it seems to work as well as selective serotonin reuptake
inhibitors (SSRIs), a popular type of antidepressant that doctors often
prescribe first to treat depression. They include fluoxetine (Prozac),
citalopram (Celexa), and sertraline (Zoloft). In addition, St. John's wort
doesn’t seem to have one of the most common side effects of
antidepressants, which is loss of sex drive.*
St. John's wort contains several chemicals, including hypericin,
hyperforin, and flavonoids. Researchers aren't exactly sure how St. John's
wort works. Some have suggested that the herb acts similar to an SSRI,
making more of the brain chemicals serotonin, dopamine, and norepinephrine
available. These neurotransmitters help improve one's mood. Scientists
thought that hypericin was responsible, but now they believe that other
chemicals in St. John's wort may help.*
Not all studies agree, however. In one study, St. John's wort was found to
be no more effective than placebo for treating depression. But these
studies should be weighed against the majority that has found St. John's
wort helps depression. For example, in the same study, Zoloft also failed
to show any benefit in treating depression. Many other studies have
compared St. John's wort to Prozac, Celexa, paroxetine (Paxil), and Zoloft,
and found that the herb works as well as the drug. Other studies are
St. John's wort has also shown a promise in treating the following
conditions, a few of which are related to depression.
Premenstrual syndrome (PMS):
An early study suggests that St. John's wort may help relieve physical
and emotional symptoms of PMS in some women, including cramps,
irritability, food cravings, and breast tenderness.*
Two studies suggest that St. John's wort, combined with black cohosh,
helps improve mood and anxiety during menopause.*
Seasonal affective disorder (SAD):
Used alone, St. John's wort has improved mood in people with SAD, a
type of depression that occurs during the winter months because of lack
of sunlight. SAD is usually treated with light therapy, and there is
some evidence that using St. John's wort together with phototherapy
works even better.*
Eczema, wounds, minor burns, hemorrhoids:
St. John's wort has antibacterial properties and may also help fight
inflammation. Applied topically (to the skin), it may relieve symptoms
associated with minor wounds and skin irritation.*
Obsessive-compulsive disorder, social phobia:
One early open-label study found that taking St. John's wort 450 mg two
times a day for 12 weeks improved OCD symptoms. But two other studies
found that St. John's wort didn’t help OCD.*
St. John's wort is a shrubby plant with clusters of yellow flowers that
have oval, elongated petals. Scientists believe it is native to Europe,
parts of Asia and Africa, and the western The United States. The plant gets
its name because it is often in full bloom around June 24, the day
traditionally celebrated as the birthday of John the Baptist. Both the
flowers and leaves are used as medicine.
What is It Made Of?
The best-studied active components are hypericin and pseudohypericin, found
in both the leaves and flowers. Researchers now think that these components
may not be responsible for St. John’s wort’s healing properties. Scientists
are now studying St. John's wort's essential oils and flavonoids.
LifeSource Vitamins St. John's Wort helps with Depression, Anxiety, PMS
Relief, Ear Infections, Cold Sores, Ulcerative Colitis, Vitiligo, Menopause
and Wound Healing. *
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as well as all Good Manufacturing Practices enforced by the FDA. CGMP's
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