Beta Glucan with Maitake Mushrooms
- 1,3/1,6 -D- Glucan
Beta Glucan: When it comes to naturally boosting the immune system
by optimizing its response to diseases and infections, beta glucans are crucial
weapons in the fight to stay healthy. But because the body doesn't produce beta
glucans naturally, the only way to get the compound is through outside sources,
this is why we at LifeSource Vitamins have added this to our line of
Beta Glucan is
a powerful immune stimulator, activating the macrophages in the immune system.
Studies have found that this product not only has a positive effect on the
macrophages, but also on B lymphocytes, natural killer cells, and suppressor T
cells. In addition to these important functions, Beta Glucan is an effective
antioxidant and free radical scavenger.*
cells play an essential role in the maintenance of the immune system. Macrophages
are the cells that recognize, engulf and destroy any cells, organisms
and substances that are not natural or required by the body (bacteria, viruses,
fungi, dead or mutated cells, etc.).
It also can
produce a number of essential cytokines that are able to stimulate the immune
system in general and boost bone marrow production. In addition to having a
huge appetite for toxins, macrophages play a pivotal role in the initiation
immune responses. Once a foreign body attacks the body, the macrophages become
activated, and a chain reaction occurs that mobilizes the entire immune
There have been
over 1,000 research papers on Beta 1,3-D Glucan since the 1960s. Research
backed by prestigious institutions such as the U.S. Food and Drug
Administration, Harvard, Tulane, Baylor, McGill, University of California,
Duke, Washington, Armed Forces Radiology Research Institute, and other
institutions all demonstrate the high immune-activating properties of Beta
Glucan. Beta Glucan has been found to stimulate or modulate macrophage cells
(leukocytes, or white blood cells).*
Mushrooms: Why add Maitake
Mushrooms? It really is a natural addition. The
Maitake mushroom has an active ingredient called beta glucan. These mushrooms
have been used in Japan for centuries, and they are believed to promote
longevity and overall well-being. It’s a polysaccharide found in other
medicinal mushrooms. The Maitake Mushroom, however contains one called
D-fraction. Researchers believe that it is this beta glucan that gives the
mushroom its healing powers. Unlike common mushrooms, Maitake’s are packed with
unbelievably healthy nutrients such as powerful antioxidants, Vitamins B, C and
also Niacin. They are also packed with minerals like iron, zinc, potassium,
selenium, protein, amino acids and fiber.
Shown to Support immune health; researched for over 2
- Activation of macrophages, expressing increased
nonspecific phagocytic ability allowing macrophages to destroy pathogens
more efficiently, frequently preventing disease.*
- Ideal for people who exercise more than the average*
Athletes, Professional Athletes in any sport, Body Builders, Runners,
anyone who over exerts continually.*
- Release of important cytokines, such as IL-1, IL-2
among others, initiating immune cascade and triggering other cell lines,
such as T-cells. Release of colony-stimulating factors, boosting bone
marrow production. *
- Cholesterol-reduction through cell activation and
- Diabetes Support*
- Blood Sugar Support*
- Helps with Radiation Support*
- A bio-active Carbohydrate
- Nourishes and stimulates the immune system*
Keeping Your Immune
system protects our bodies against viruses, bacteria, fungi, parasites, and
much more. It is a miraculous complex network of organs that contain cells that
recognize and destroy foreign invaders. Some individuals, because of age, poor
nutrition, stress, unhealthy lifestyle, or environmental toxins have a
compromised immune system.* Specialized
white blood cells called macrophages, and they are the first line of defense of
your immune system. Macrophages are essentially the "guard dogs" of
your immune system, and constantly on alert.
What do these Beta Glucans do?
One of the
health benefits is boosting the immune system. It actually works by activating
the white blood cells, specifically neutrophils and macrophages. These white
blood cells are the immune system's line of defense against pathogens and
foreign invaders in the body. Neutrophils and macrophages activated by beta
glucan aid in recognizing and destroying tumor cells, accelerate repair of damaged
tissue, help remove cellular waste caused by oxidative damage, and help
activate the immune system's other components. *
It is a soluble
fiber that helps decrease the absorption of sugar that comes from the diet.
Several studies have suggested the value of beta glucan in keeping blood sugar
levels under control but more studies are needed in order to verify this data.
Strong evidence shows that people who incorporated more foods that produce a
low glycemic response in their diets had a significant improvement in diabetes
Due to the
gel-like substance that is produced from beta glucan when it is dissolved in
the digestive tract, it is quite effective in reducing bad cholesterol or LDL
and the overall cholesterol level in the body. Lower cholesterol levels means a
decreased chance for developing heart diseases like coronary heart disease. *
Heart disease study:
Randomized controlled crossover study of the effect of a highly
beta-glucan-enriched barley on cardiovascular disease risk factors in mildly
Department of Medicine, the Human
Nutrition & Metabolic Unit, University of Auckland, New Zealand.
Soluble-fiber beta-glucan derived
from oats can reduce cardiovascular disease (CVD) risk through reductions in
total and LDL cholesterol. Barley-derived beta-glucan may also improve serum
cholesterol, but large quantities are required for clinical significance. This
trial investigated whether a beta-glucan-enriched form of barley can favorably
modify cholesterol and other markers of CVD and diabetes risk. Eighteen mildly
hyperlipidemic men were randomly assigned in this single-blind, 2 x 4-wk trial
to either the treatment arm or the control arm. After a washout period of 4
weeks, dietary regimens were crossed over. There was no significant change in
total, LDL, or HDL cholesterol or in triacylglycerol, fasting glucose, or
postprandial glucose when analyzed between treatments. The effect of
beta-glucan -enriched barley on lipid profile was highly variable between
subjects, and there was no evidence of a clinically significant improvement in
CVD risk across this group of mildly hyperlipidemic men.
Effects of oat beta-glucan on innate
immunity and infection after exercise stress.
Med Sci Sports Exercise. 2004.
To test the effects of oat beta
glucan on respiratory infection, macrophage antiviral resistance, and NK
cytotoxicity it was fed to mice in the drinking water for 10 days before
intranasal inoculation of HSV-1 or sacrifice. Our data suggest that daily
ingestion of beta glucan may offset the increased risk of upper respiratory
infection associated with exercise stress, which may be mediated, at least in
part, by an increase in macrophage antiviral resistance.
One of the most remarkable oral
studies with beta-1,3-glucan was done at the US Armed Forces Radiobiology
In a well-controlled study, 70% of
rats given a lethal dose of radiation were completely protected from radiation
effects when given a dose of yeast beta glucan by mouth AFTER the radiation16. Dr. Myra Patchen discovered that beta-glucan is also a free
radical scavenger. It is able to protect blood macrophages from free radical
attack during and after the radiation allowing these cells to continue to carry
their important functions in the irradiated body and release factors important
to the restoration of normal bone marrow production. Patchen
ML, D'Alesandro MM, Brook I, Blakely WF, McVittie TJ: Glucan: mechanisms
involved in its "radioprotective" effect.. J Leuc Biol 1987; 42:
6 Health Benefits of Maitake
The Maitake mushroom has
been prized in Asia for thousands of years for its health benefits. The
Japanese word "Maitake" means "dancing mushroom," a name derived
from the reaction of people having found these mushrooms, which were actually
worth their weight in silver. Modern research on the Maitake mushroom only
began in Japan in the 1980s and has just recently begun to be conducted to the
United States. Most research has been done on the extract rather than the fresh
mushroom and tests on humans are limited.
Maitake mushrooms are highly sought after for their
anti-cancer properties. They are abundant in polysaccharides and
polysaccharide-protein complexes that the body uses to fortify the immune
system. The mushroom’s beta-glucan content works to promote important immune
system functions, effectively activating white blood cells that fight off
microorganisms that cause disease, including cancer. Maitake mushrooms enhance
the activity of cells, inducing the production of interleukins and other
lymphokines that have chemo protective effects, slow tumor growth, and help to
inhibit the spread of cancer.
Immune System Support
Maitake mushrooms grow primarily in northeastern Japan and the United States,
and are esteemed by traditional Chinese medicine for fighting disease and
improving immunity. Regular consumption of Maitake enhances the immune system
as well as lowers blood pressure. The most effective ingredient in the mushroom
is its beta-glucan, a polysaccharide compound that boosts the immune system
through the activation of macrophage cells, natural killer cells and T-cells.
These cells play an important role in building general immunity and preventing
free radicals from harming the body's systems.
Blood Sugar Control
The consumption of Maitake mushrooms may regulate blood sugar levels and blood
lipid levels. The polysaccharide compounds that promote the strength of the
immune system are also effective in helping to regulate blood pressure,
glucose, insulin and lipids. This effect is especially beneficial for people
with diabetes or hypoglycemia. People with Type 2 Diabetes may also benefit
from Maitake mushrooms. Scientists have studied a specific, high-molecular
polysaccharide in Maitake called the X-fraction. Research results suggest that
Maitake mushrooms can reduce insulin resistance and increase insulin
Lower Blood Pressure
Research on animals suggests that Maitake may help lower blood pressure in
people. One study gave hypertensive rats a 5% Maitake mushroom powder and
observed a reduction in blood pressure. Similar results were seen from another
study on rats, in which Maitake lowered blood pressure from 200 to 115 mm Hg in
just 4 hours. In an unpublished trial on humans, eleven patients with
hypertension took 500 mg of Maitake mushroom pills twice a day. A mean decrease
in diastolic blood pressure of approximately 8 mm Hg and a mean decrease in
systolic blood pressure of about 14 mm Hg were reported.
In one study on hyperlipidemic rats, Maitake changed lipid metabolism through
inhibiting the aggregation of liver lipids and the raising of serum lipids.
Similar results were seen in rats fed a high-cholesterol diet. In another
study, rats given powdered mushroom preparations saw a drop in both total
cholesterol and very low-density lipoprotein-cholesterol.
Maitake mushrooms can promote weight loss and decrease obesity when combined
with light exercise. Studies on overweight rats fed Maitake powder found that
after 18 weeks, they had lost weight compared with controls. They contain no
cholesterol, no fats and are very low carbohydrates. Additionally, the high
lean protein content of mushrooms helps burn cholesterol in digestion.
& Beta Glucan
The effects of concentrated barley beta-glucan on blood lipids in a
population of hypercholesterolaemic men and women. Br J Nutr. 2007.
University of Minnesota, Medical School, Department of Family Medicine and
Community Health, Minneapolis, MN, USA.
We evaluated the LDL-
cholesterol lowering effect of a concentrated barley beta-glucan extract as a
vehicle to deliver this potential health benefit of barley. In a 10-week
blinded controlled study, subjects were randomized to one of four treatment
groups or control. Treatment groups included either high molecular weight or
low molecular weight barley beta-glucan extract at both 3 and 5 g doses.
Treatment was delivered twice per day with meals in the form of two functional
food products: a ready-to-eat cereal and a reduced-calorie fruit juice
beverage. After 6 weeks of treatment the mean LDL- Cholesterol levels fell by
15 % in the 5 g HMW group, 13 % in the 5 g LMW group and 9 % in both the 3 g/d
groups, versus baseline. Similar results were observed for total cholesterol.
HDL-C levels were unchanged by treatment.
significantly improves HDL Cholesterol and diminishes LDL Cholesterol and
non-HDL cholesterol in overweight individuals with mild hypercholesterolemia. Am J Ther. 2007. Center for Metabolic and
Endocrine Research, The University of Zulia, Maracaibo, Venezuela.
To investigate the
effect of bread formulated with 6 g of beta-glucan (oat soluble fiber) on serum
lipids in overweight subjects with high cholesterol levels. Thirty-eight male
subjects who were eligible for the study ate an isocaloric diet for a 1-week
period. They were then divided into 2 groups: group A, who were maintained on
American Heart Association (AHA) Step II diet, including whole wheat bread, and
group B, who were maintained on AHA Step II diet containing high levels of
monounsaturated fatty acids plus bread containing 6 grams of beta-glucan
(Nutrim-OB) for 8 weeks. There was a significant increase in plasma high
density lipoprotein cholesterol in the beta-glucan group, but there was no
change in group B. There was a significant reduction in total cholesterol in
the 2 groups to approximately the same extent. Plasma low density lipoprotein
(LDL) cholesterol also decreased significantly in the two groups; however, the
beta-glucan fortified diet was significantly more effective. The beta-glucan
diet also decreased fasting plasma glucose, whereas the other diet had no
effect. Six grams of beta-glucan from oats added to the AHA Step II diet and
moderate physical activity improved lipid profile and caused a decrease in
weight and, thus, reduced the risk of cardiovascular events in overweight male
individuals with mild to moderate hypercholesterolemia.
Dr. Ronald Mensink, of
Maastricht University tested 25 healthy subjects who drank a fruit drink
containing beta-glucan from oats and 22 healthy subjects who drank a fruit
drink containing 5 grams of rice starch, which served as a placebo. All of the
subjects drank the juice every day for five weeks. Compared with the placebo
group, total cholesterol was reduced by 5 percent and LDL cholesterol by 7.7
percent in the beta-glucan group. The investigators also found that the
beta-glucan drink decreased cholesterol absorption and increased synthesis,
without affecting levels of fat-soluble antioxidants. American Journal of
Clinical Nutrition, March 2006.
Beta Glucan incorporated
into a fruit drink effectively lowers serum LDL- cholesterol concentrations.
American Journal of Clinical Nutrition, 2006
We examined the effects
of a beta glucan -enriched fruit juice on serum lipids and lipoproteins and on
markers of cholesterol absorption (serum concentrations of plant sterols) and
synthesis (serum concentrations of lathosterol). Beta Glucan lowers serum
concentrations of total and LDL cholesterol when incorporated into a fruit
drink without affecting plasma concentrations of lipid-soluble antioxidants.
beta-glucans improve metabolic and anthropometrics variables in well controlled
type 2 diabetic patients. Am J Ther. 2003.
A total of 16 male, well
controlled type 2 diabetes patients were divided into two groups of eight; one
group received the diet based on the American Diabetic Association's nutrition
recommendations, and the other was fed a modified, low-calorie diet containing
a fat replacer (beta-glucans derived from oats) and the sweeteners, sucralose
and fructose. Both diets produced significant improvements in weight, body mass
index, lipid profile, basal glucose, and HbA1C. However, the beta glucan diet
was superior to the American Diabetic Association's diet in improving metabolic
and anthropometric profile: greater increase in HDL cholesterol and larger
decreases in HbA1C, weight, and body mass index.
with beta-glucan enriched oat bran increases faecal concentration of carboxylic
acids in healthy subjects. European Journal of Clinical Nutrition 2007; Applied
Nutrition and Food Chemistry, Department of Food Technology, Center for
Chemistry and Chemical Engineering, Lund University, Lund, Sweden.
especially butyric acid, have been suggested to counteract colonic diseases,
such as ulcerative colitis and colon cancer. To elucidate how the colonic
concentration of carboxylic acids in healthy subjects is influenced by dietary
supplementation with oat bran, and whether the concentration varies over time
and during consecutive days. Twenty-five healthy subjects were given 40 g
beta-glucan enriched oat bran per day, corresponding to 20 g dietary fiber, in
4 slices of bread. After 12 weeks, the concentrations of acetic, propionic and
isobutyric acid were higher and that of lactic acid lower. The variation
between individuals was considerable, whereas in the same individuals there was
little variation. Oat bran increased the fecal concentration of carboxylic
acids after 8 weeks, indicating an increased concentration also in the distal
colon. The concentration of all main acids increased, except for lactic acid,
which decreased. Oat bran may therefore have a preventive potential adjunct to
Diabetes and blood sugar
Beta glucan may be
helpful in blood sugar control. The addition predictably reduces the glycemic
index. In a 50 g carbohydrate portion each gram of beta-glucan reduces the
glycemic index by 4 units, making it a useful functional food component for
reducing postprandial glycemia. It has also been tested for cholesterol level
Studies have found that Beta Glucan not only has
a positive effect on the macrophages, but also on B lymphocytes, natural killer
cells, suppressor T cells and free
LifeSource Vitamins Ultra Beta Glucan with Maitake
Mushrooms, Beta - 1,3/1,6 -D- Glucan, When it comes to naturally boosting the
immune systems by optimizing its response to diseases, beta glucans are crucial
weapons in the fight to stay healthy.
Vitamins product exceeds the standards and requirements set forth in the FDA’s
Code of Federal Regulation (21 CFR, 111) Current Good Manufacturing Practices
in the USA, with ALL USA Ingredients!
E-mail Us: info@LifesourceVitamins.com
or Call Us: 800.567.8122
We Are Built on Compassion - Driven
by Faith & Powered by God!
It can be overwhelming we know.
Call us, we will walk you through what supplements will help you and
which ones you really don’t need. It’s what we do!
*Disclaimer: None of the above statements have been evaluated by the FDA. These
products are not intended to diagnose, treat, cure or prevent any disease. As
always, consult your physician before taking any and all supplements.
LifeSource Vitamins. Individual results may vary.
Disclaimer: All the information contained throughout this website is based upon the
opinion of the founder of LifeSource Vitamins Bruce Brightman, and the entire
team at LifeSource Vitamins whose relentless research and studies have been
ongoing on since 1992. Other articles
and information are based on the opinions of the authors, who retains the
copyright as marked on the article. The
information on this site is not intended to replace your health care
professional, but to enhance your relationship with them. Doing your own studying and research and
taking your health care into your own hands is always best, especially in
partnership with your health care professional.
If you are pregnant, nursing, taking medications, or have any medical
conditions, always consult your health care professional before taking
supplements based on the information on this site.
Ultra Beta Glucan with Maitake Mushrooms, Beta - 1,3/1,6 -D- Glucan, When it
comes to naturally boosting the immune systems by optimizing its response to
diseases, beta glucans are crucial weapons in the fight to stay healthy.*|