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Restless Leg Syndrome - Conditions & Cures Info with Proven Effective Supplements Listed
Restless Leg Syndrome - Conditions & Cures Info with Proven Effective Supplements Listed

MTHFR Mutation

Conditions & Cures
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  • Discomfort in the legs such as pulling, crawling, throbbing, or other abnormal sensations that lead to an uncontrollable urge to move them
  • Symptoms occurring on both sides, and, less often, affecting other body parts, such as arms, trunk, or head
  • In 80% of sufferers, an involuntary jerking or twitching of the legs during sleep, causing disrupted sleep and daytime fatigue


  • Genetics is thought to be the cause of primary RLS. Secondary causes include:
  • Iron deficiency (approximately 25% of sufferers)
  • Folate deficiency (or an MTHFR gene mutation)
  • Magnesium deficiency
  • Amyloidosis
  • Diabetes
  • Kidney disease
  • Lumbosacral radiculopathy
  • Lyme disease
  • Monoclonal gammopathy
  • Pregnancy
  • Rheumatoid arthritis
  • Sjogren's syndrome
  • Venous disorder
  • Certain pharmaceuticals, e.g., antihistamines such as diphenhydramine (Benadryl), antidepressants, lithium, beta-blockers, and antipsychotics

Recommended Food

  • Eat a whole-food, plant-based diet that is rich in antioxidants.
  • Cold-water fish and their omega-3 fatty acids reduce brain inflammation.
  • Food sources of magnesium are important. Consume more magnesium-rich foods such as pumpkin seeds, spinach, quinoa, black beans, and navy beans.
  • If your potassium is low then good food sources include tomatoes, tomato juice, bananas, avocados, yogurt, and broccoli.

Foods to Avoid

It is important to avoid caffeine and alcohol, which can worsen symptoms.

The top 7 vitamins and supplements shown to help Restless Leg Syndrome:

Prescription for Natural Cures by James F. Balch, M.D. and Mark Stengler, N.M.D.

Super Prescription # 1 Iron - LifeSource Product A typical dose is 50 to 100 mg of chelated iron daily.

Super Prescription # 2 Folate - LifeSource Product Take 400 mcg if your level is low or you have a MTHFR gene mutation.

Super Prescription # 3 5-HTP - LifeSource Product Take 100 to 200 mg at bedtime.

This amino acid increases serotonin, which relaxes the nervous system.

Super Prescription # 4 Magnesium - LifeSource Product Take 400 to 500 mg each evening. It relaxes your nervous system and muscles.

Super Prescription # 5 Valerian Root - LifeSource Product Take 800 mg at bedtime. Research has shown it to benefit RLS.

Super Prescription # 6 N-acetyl tyrosine - LifeSource Product Take 500 mg each evening. Increases dopamine levels and reduce restless legs.

Super Prescription # 7 Pycnogenol - LifeSource Product Take 100 mg at bedtime. Improves circulation to the legs and reduces inflammation.

General Recommendations

Those with Restless Leg Syndrome (RLS) should definitely try acupuncture. Studies have shown benefit. While acupuncture may not cure RLS, it can help reduce symptoms.

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*Disclaimer: None of the above statements have been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. As always, consult your physician before taking any and all supplements. LifeSource Vitamins. Individual results may vary.

Disclaimer: All the information contained throughout this website is based upon the opinions of the founder of LifeSource Vitamins, Bruce Brightman, and the entire team at LifeSource Vitamins whose relentless research and studies have been ongoing since 1992. Other articles and information are based on the opinions of the authors, who retain the copyright as marked in the article. The information on this site is not intended to replace your health care professional, but to enhance your relationship with them. Doing your own studying and research and taking your health care into your own hands is always best, especially in partnership with your health care professional.

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