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OPC 200 mg — 90 Vegetarian Capsules — Cardiovascular, Vascular & Antioxidant Support*
LifeSource Vitamins OPC 200 mg supplies clinically studied oligomeric proanthocyanidins (OPC) from standardized grape seed extract to support healthy circulation, vascular elasticity, lipid balance, and powerful antioxidant defense. Produced in FDA-registered, GMP-certified facilities and third-party tested for identity, potency & purity.*
• Supports healthy blood pressure* — Randomized trials report BP improvements with grape seed proanthocyanidins in adults with prehypertension or cardiometabolic risk. (Nutrients 2019)
• Overall BP-lowering across trials* — Meta-analysis of 16 RCTs found reductions in systolic and diastolic BP. (Medicine 2016)
• Enhances endothelial/vascular function* — Human studies and meta-analyses show improved flow-mediated dilation and vascular elasticity. (Pharmacol Res 2022)
• Improves lipid profile (context)* — Evidence for favorable effects on LDL, total cholesterol and triglycerides in dyslipidemia. (Br J Nutr 2020)
• Boosts antioxidant capacity* — Clinical data show improved oxidative-stress markers. (Medicine 2018)
• Insulin sensitivity & metabolic markers* — RCTs report reductions in insulin/HOMA-IR and improvements in cardiometabolic endpoints in at-risk populations. (Diabetes Metab Syndr 2021; Nutrients 2024)
• Skin tone/brightening (adjacent)* — Oral proanthocyanidin-rich extracts improved chloasma/melasma outcomes in controlled studies. (2004; 2009; Review 2024)
• Leg comfort/venous flow (pilot)* — Imaging data suggest improved vena cava flow metrics with grape seed proanthocyanidins. (2022)
• Oral/gum health (adjacent)* — GSE mouthwash reduced plaque bacteria in a clinical trial. (J Clin Diagn Res 2022)
• Exercise oxidative stress (athletes)* — Improved antioxidant biomarkers in RCTs. (2016)
• Platelet balance (caution)* — Human/experimental data suggest modulation of platelet aggregation; consult your clinician if using anticoagulants/antiplatelets. (2013–2014)
• Overviews from NCCIH/NIH and academic reviews summarize safety and potential uses of standardized grape seed extract in adult wellness programs.*
• Help maintain healthy blood pressure & smooth circulation*
• Targeted endothelial/vascular support with standardized OPC*
• Robust antioxidant defense against daily oxidative stress*
• Supports healthy LDL, triglycerides & cardiometabolic balance*
• If using blood thinners or have bleeding concerns, consult your clinician first*
• 3rd-party lab tested for identity, potency & purity
Adults take 2 capsules daily with a meal, or as directed by your healthcare professional. If pregnant, nursing, taking medications (especially anticoagulants/antiplatelets), or have a medical condition, consult your physician.*
• Serving Size — 2 Vegetarian Capsules
• Servings Per Container — 45 (90 capsules total)
• Key Active — OPC (Oligomeric Proanthocyanidins) 200 mg per serving (from standardized grape seed extract)
• Other Ingredients — Vegetarian cellulose capsules
• Free From — Non-GMO; gluten-free*
• Quality — Third-party tested for identity, potency & purity
3rd-Party Testing: Every batch is verified by independent labs for identity, potency, and purity. Click here to see our 3rd-party testing.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
OPC 200 mg — standardized grape seed proanthocyanidins for circulation, lipids & antioxidant defense — third-party tested quality. Clinically Studied Ingredients — NIH/PubMed!*

*Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before taking any supplements. Individual results may vary. This information is not intended to replace your healthcare provider but to support and enhance that relationship. You are encouraged to do your own research and take an active role in your health decisions. If you are pregnant, nursing, taking medications, or have any medical conditions, consult your healthcare professional before using any supplements discussed on this site.