What Is D, L-Phenylalanine Capsules?
Phenylalanine is an essential amino acid, which means your body can’t
produce sufficient amounts and requires it from an external source.
It’s converted to L-tyrosine in the liver, which is then converted into
dopamine, norepinephrine and epinephrine (adrenaline) hormones that can
become depleted for a variety of reasons. Replenishing norepinephrine
in the brain can support brain health.
The neurotransmitters produced from phenylalanine supplementation bring
a wide range of cognitive health benefits.
D, L-Phenylalanine Benefits
Supports production of L-tyrosine, which is used to make dopamine,
norepinephrine & epinephrine
Helps promote healthy mood & sleep
Supports healthy cognitive function
Provides protection for brain cells
Essential Nutrient to Support Mood and Cognitive Health
D,L-phenylalanine is a 50/50 mixture of its two stereoisomers that
can be converted to L-tyrosine in the liver, which is then used to
make dopamine, norepinephrine and epinephrine. In addition to
acting as a neurotransmitter that supports healthy mood and sleep,
norepinephrine is known to protect brain cells by promoting a
healthy inflammatory response, inhibiting oxidative stress and
supporting healthy neuronal growth.
Phenylalanine is an essential amino acid that can be converted to
L-tyrosine in the liver. Tyrosine is used in the nervous system to
make a class of neurotransmitters called catecholamines: dopamine,
norepinephrine and epinephrine. Epinephrine, made from tyrosine in
the adrenal medulla, functions as a neurohormone and is known as
In addition to acting as a neurotransmitter that supports
healthy mood and sleep, norepinephrine is now known to protect
brain cells by promoting a healthy inflammatory response,
inhibiting oxidative stress and supporting healthy neuronal
growth and connectivity.2
Dopamine, though long associated with more primal aspects of
brain function linking behaviors to rewards, is recognized now
as a mediator of higher-order cognitive capacities.3,4 The
diminishment in brain catecholamine production that occurs with
aging may be a contributing factor in normal age-related
cognitive decline.3,5 Providing catecholamine precursors can
help support healthy cognitive function.6 The enzyme that
catalyzes the conversion of tyrosine to dopamine may work more
efficiently if its co-factors (vitamins B6 and C) are
Phenylalanine supplementation supports healthy neurotransmitter
synthesis and clinical trials suggest it may promote positive
Since both norepinephrine and epinephrine can cause smooth
muscle (arterial) contraction, care with blood pressure should
be taken when supplementing with phenylalanine.
D, L-Phenylalanine is a 50/50 mixture of its two stereoisomers.
. 2007;137(6 Suppl 1):1539S-1547S; discussion 1548S.
. 2016;139 Suppl 2:154-178.
Neurosci Biobehav Rev
Neurosci Biobehav Rev
Eur J Nucl Med Mol Imaging
J Psychiatr Res
Biochem Biophys Res Commun
Biochim Biophys Acta Gen Subj
Arch Psychiatr Nervenkr (1970)
J Neural Transm
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