LifeSource Vitamins Skullcap Extract — 500 mg per Serving, Liquid Extract, 1 fl oz — Supports Natural Relaxation & Restful Sleep*
Organic Scutellaria lateriflora (American Skullcap) in a fast-absorbing liquid form. Each serving delivers 500 mg herb weight equivalence to support calm relaxation, balanced mood, and restorative sleep. Produced in FDA-registered, GMP-certified facilities and 3rd-party tested for identity, potency & purity.*
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from 39 leading health organizations and insights from 20 top global universities to ensure our guidance aligns with credible science.*
Clinically Studied Benefits
✓ Supports calm mood & relaxation — Randomized, double-blind, placebo-controlled, crossover trial in healthy adult volunteers showed reduced Total Mood Disturbance with skullcap extract.
NIH/PubMed — Brock et al., 2014
Additional / Promising Evidence
✓ Mechanism: GABA-A receptor modulation — Human-relevant mechanistic evidence indicating skullcap flavonoids interact with benzodiazepine sites on GABA_A receptors (non-clinical).
NIH/PubMed — Awad et al., 2003
✓ Neuroprotective antioxidant activity — Skullcap extracts protected neural tissue models against oxidative stress (non-clinical).
NIH/PubMed — Lohani et al., 2013
✓ Potential cognitive support — Early experimental literature suggests neuroprotective effects relevant to memory/aging (non-clinical).
NIH/PubMed
University-Led & Academic Studies
✓ GABA mechanism (phytochemistry & behavior) — University of Ottawa/Ottawa-Carleton Institute team detailed flavonoids and GABA-linked anxiolytic activity (non-clinical).
NIH/PubMed — Awad et al., 2003
✓ Antioxidant/neuroprotection pathways — Academic groups reported skullcap extract antioxidant and DNA-protective effects (non-clinical).
NIH/PubMed — Lohani et al., 2013
Global Evidence & Reviews
✓ National Center for Complementary and Integrative Health (NCCIH) — U.S. National Center overview on skullcap’s safety and traditional uses; notes rare hepatotoxicity reports often with combinations/adulterants.
NIH/NCCIH
✓ LiverTox (NIH/NLM) — Safety profile summary; rare liver injury reports, frequently confounded by other herbs/adulterants.
NIH/LiverTox
We monitor research from leading institutions —
Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients
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Organic Skullcap (Scutellaria lateriflora) — A traditional nervine herb studied for relaxation and calm mood in adults, with mechanistic support via GABA pathways and antioxidant activity (see studies above).* (NIH/PubMed — Brock et al., 2014)
Brief Benefit Bullets
- Calms the nervous system and eases mild tension*
- Supports natural, restorative sleep without drowsy after-effects*
- Provides antioxidant and neuroprotective activity*
- Contains flavonoids that interact with calming GABA receptors*
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3rd-party lab tested for purity & potency
Suggested Use
Take 1 mL (approx. 30 drops) daily, preferably in the evening, or as directed by your healthcare professional. Shake well before use. If pregnant, nursing, taking medications, or have a medical condition, consult your physician.*
Product Specifications
- Serving Size — 1 mL (30 drops)
- Servings Per Container — 30
- Amount Per Serving — 500 mg herb weight equivalence
- Ingredient — Organic Fresh Skullcap Herb (Scutellaria lateriflora)
- Herb Strength Ratio — 1:2
- Other Ingredients — Grain Alcohol (64–74% by volume), Deionized Water
- Form — Liquid herbal extract
- Quality — Third-party tested for identity, potency & purity
3rd-Party Testing: Every batch is independently verified for identity, potency, and purity.
See our testing program.
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Skullcap Extract — organic Scutellaria lateriflora liquid extract for natural relaxation, calm mood, and restful sleep. Fast-absorbing. Clinically Studied Ingredients — NIH/PubMed!*
