List of Common Uses for Nutritional Sulfur (MSM)
Treat and Supports Osteoarthritis and Joint Pain*
Treats Digestive Problems like Leaky Gut Syndrome*
Helps with Skin Problems such as: Rosacea, Allergies & Wounds*
Shown tom Lower Muscle Pain and Spasms*
Supports Hair Growth*
Helps the Body Adapt to Stress*
Also May Be Helpful for:
Allergies (Dust, Food, Mites, Pollen)*
Carpal Tunnel Syndrome*
Enhances Vitamin C*
Free radical damage*
Hair growth and appearance*
Heartburn / Hyperacidity*
Pets (silky coat/skin disorders)*
Urinary tract disorder*
Among numerous other reported and studied benefits, MSM:
• May replace expensive drugs/nutrients to treat arthritis, gastric
• Helps remove excess mercury from the body and maintains the health of
skin, hair, nails
MSM (Methylsulphonylmethane) is a natural form of organic sulfur found in
all living organisms. This natural compound, researched since 1979,
provides the chemical links needed to form and maintain numerous different
types of tissues found in the human body, including connective tissue such
as articular cartilage. While MSM is a natural component of almost all
fresh fruits, vegetables, seafood, and meat, food-processing methods reduce
sulfur levels, making supplementation more important than ever.
LifeSource’s MSM is tested to meet a minimum 99.7% purity.
What is MSM?
Methyl-sulfonyl-methane (MSM) is a naturally occurring sulfur compound
found in our bodies as well as in many common beverages and foods,
including milk, coffee, tea and green vegetables. In its purified chemical
form, it is an odorless, essentially tasteless, white, water-soluble
crystalline solid. It is one of the safest substances in biology, similar
in toxicity to water.
• MSM contains 34% elemental sulfur, by weight.
• MSM is a non-animal-based nutritional supplement and is an all-natural
source of MSM.
Naturally-occurring sulfur, such as that found in MSM, is not similar to
inorganic sulfides, sulfites and sulfates to which many people are
allergic. In other words, people who are allergic to sulfa drugs will
not normally react to MSM or dietary sulfur.
MSM is an organic form of sulfur found in all living organisms. It is the
fourth most abundant mineral in the human body (tenth most abundant in the
known universe) and is found in every cell. Sulfur provides the chemical
links needed to create collagen, which forms and holds the molecular
structure of connective tissue. It forms the disulfide bonds in connective
tissue that are the links in the glycosaminoglycan chains that form
cartilage. MSM is an essential nutrient, not only for connective tissue but
also for all other tissues in the human body. Unfortunately, modern
food-processing methods greatly reduce natural MSM levels in foods, so very
little is obtained from the diet these days, unless your diet is rich in
unprocessed milk, vegetables and grains. Sulfur is abundant in chondroitin
sulfate and hyaluronic acid, two constituents that support healthy joint
Usage and Toxicity
Due to its positive effects maintaining healthy cell formation, 2000 mg to
6000 mg of supplemental MSM daily is recommended. Of course, the optimum
daily dosage of MSM depends largely on body size, age and the nature and
severity of any deficiency symptoms you may be experiencing. Since vitamin
C provides a positive synergistic it should be taken along with MSM.
MSM ranks in the "extremely low" toxicity category with a toxicity profile
similar to that of water. When oral supplements are taken, the body will
distribute MSM where it is needed. After about 12 hours, any excess amounts
will be flushed out of the body. MSM is a member of the sulfur family,
should never be confused with sulfa drugs to which some people are
MSM should be supplemented with vitamin C to aid the production of
connective tissue (elastin and collagen).
10.01.04 -- MSM: Helping Alleviate Allergy Symptoms
By Greg Arnold, July 14, 2004, Abstracted from “A multicentered, open-label
trial on the safety and efficacy of methylsulfonylmethane in the treatment
of seasonal allergic rhinitis” in the Journal of Alternative and
Complementary Medicine 2002; 8(2): 167-73
Seasonal allergic rhinitis (SAR), a common clinical expression of an atopic
reaction (genetic predisposition) to inhaled allergens, affects more than
23 million Americans annually. These allergic reactions can range from mild
daily symptoms to debilitating headaches, severe nasal congestion that may
lead to sinus infection and difficulties breathing.
Current prescription and over-the-counter medications act mainly by
inhibiting histamine, the primary inflammatory mediator in allergic
reactions. Unfortunately, patients taking these medications experience
symptoms that include sedation, dizziness, rings in the ears, fatigue,
insomnia, tremors, nausea, constipation, and diarrhea.1 The cornucopia of
side effects has spawned a search for alternative therapies that will give
similar results without the side effects. One such supplement showing
promise is methylsulfonylmethane (MSM).
Researchers had 50 subjects consume 2600 mg of MSM orally per day for 30
days. The subjects were evaluated using a Seasonal Allergy Symptom
Questionnaire (SASQ) at 0, 7, 14, 21, and 30 days. Researchers also
measured C-reactive protein and immunoglobulin at the beginning and end of
Results were observed as early as day 7, where upper and total respiratory
symptoms were reduced significantly when compared with the beginning of the
study. By week 2, energy levels had “increased significantly.” By week 3,
lower respiratory symptoms were significantly improved. Even more
encouraging was that all improvements observed in the subjects were
Not only did the researchers recommend MSM for allergies (2600 mg/day for
30 days), they observed that “few side effects are associated with the use
of this compound.”
1 Hardman JG. Goodman & Gilman’s The Pharmacological Basis of
Therapeutics. 9th ed. New York, McGraw-Hill, 1996
02.02.06--MSM Alleviates Arthritis Pain
Healthnotes Newswire (February 2, 2006)—Methylsulfonylmethane (MSM), a
naturally occurring sulfur-containing compound, may help decrease joint
pain and improve physical functioning in people with osteoarthritis (OA) of
the knee, reports Osteoarthritis and Cartilage (2005 Nov 22 [E-pub ahead of
By Kimberly Beauchamp, ND
OA is a chronic, degenerative disease of the cartilage that lines and
cushions the joints. It is more common in people over age 45. Although any
joint may be affected, OA most frequently develops in the hips, knees,
spine, and feet. When OA affects the knee joint, the progressive loss of
cartilage can be seen on an x-ray as a narrowed space between the bones
that surround the joint. Bits of damaged cartilage may also break off and
enter the joint space, limiting motion and causing considerable pain. Risk
factors for OA development include having a family history of the disease,
being overweight, and overusing or having a previous injury of a joint.
Acetaminophen (Tylenol) and nonsteroidal anti-inflammatory medications
(NSAIDs) such as ibuprofen (Advil) may be used to decrease the pain
associated with OA. Sometimes corticosteroid injections are given directly
into the joint to decrease swelling. Unfortunately, these treatments do not
slow the disease progression. In addition, corticosteroid injections may
cause more thinning of the cartilage and damage the tendons surrounding the
joint, and long-term use of NSAIDs increases the chance of developing
gastric ulcers. For these reasons, safer alternatives to these medications
are being sought.
MSM is a popular remedy for OA pain that is often found in supplements also
containing glucosamine sulfate and chondroitin sulfate. A recent study
found that glucosamine and chondroitin alleviate OA pain at least as well
as the prescription medication Celebrex. Previous trials suggest that MSM
may decrease inflammation and help repair connective tissue (such as
cartilage), but there is little research on its usefulness for treating OA.
In the new study, 40 men and women between ages 40 and 76 with OA of the
knee were given either 6 grams of MSM per day for 12 weeks or a placebo.
The people rated their level of pain, stiffness, physical functioning
(ability to get around and perform daily activities), and overall symptoms
before the study and after 2, 4, 8, and 12 weeks. The people and their
physicians also gave their overall impression of the state of their
arthritis before and after the study and also rated their response to
treatment. Blood and urine tests were performed to assess the safety of MSM
and to investigate the possible ways it works in the body.
The level of pain decreased significantly and physical functioning improved
after 12 weeks in the MSM group compared with the placebo group. Changes in
stiffness and overall symptoms were similar in the two groups, and there
were no differences between the groups in overall response to treatment.
MSM did not appear to raise blood pressure, nor did it adversely affect
cholesterol levels, blood clotting, or measures of kidney, nervous system,
liver, or blood-cell health. Side effects were generally mild and were
similar between the two groups.
The results of this investigation suggest that MSM may be a useful adjunct
in the treatment of OA.
Kimberly Beauchamp, ND, earned her bachelor’s degree from the University of
Rhode Island and her Doctorate of Naturopathic Medicine from Bastyr
University in Kenmore, WA. She cofounded South County Naturopaths in
Wakefield, RI. Dr. Beauchamp practices as a birth doula and lectures on
topics including whole-foods nutrition, detoxification, and women’s health.
02.24.06 -- MSM Found to Provide Short-Term Relief for Arthritic Knee
By Greg Arnold, DC, CSCS, February 15, 2006, abstracted from “Efficacy of
methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot
clinical trial” published online in Osteoarthritis and Cartilage
As the leading cause of disability in the U.S., Osteoarthritis (OA) limits
the everyday activities of more than 7 million Americans1 and can be
associated with significant restrictions on quality of life.2 As a result,
a number of options are available for patients to help control their
arthritis pain, including conservative measures like over-the-counter
medications such as aspirin and ibuprofen(3,4) and more drastic measures
like surgery.5 Even the use of complementary and alternative medicine (CAM)
has increased over the years to help treat OA.6
When it comes to nutritional supplementation in the treatment of OA, three
such supplements receiving attention are glucosamine, chondroitin, and
methylsulfonylmethane (MSM). Glucosamine and chondroitin sulfate can help
both prevent and treat OA7 by reducing inflammation, stimulating the
synthesis of proteoglycans and hyaluronic acid and reducing the synthesis
of nitric oxide and cell death of cartilage cells.(8,9,10)
MSM has undergone numerous trials in the treatment of OA(11,12,13) and as a
result, has become an extremely popular supplement for arthritic and
rheumatic pain. In 2003 alone, the retail sales of MSM as a single
ingredient were $115 million.14 Now a new study15 has found that MSM can
help provide short-term pain relief for OA in the knee.
In the study, 50 men and women aged 40–76 years with knee OA pain took
either MSM 3 g or placebo twice a day for 12 weeks (6 g per day total). To
measure outcomes, researchers used the Western Ontario and McMaster
University Osteoarthritis Index visual analog scale (WOMAC), patient and
physician global assessments (disease status, response to therapy), and
SF-36 (overall health-related quality of life).
They found that compared to placebo, MSM produced “significant decreases”
in WOMAC pain and physical function impairment with no notable changes in
WOMAC stiffness and total symptoms scores. MSM also produced “improvement”
in performing activities of daily living when compared to placebo on the
While concluding that “MSM (3 g twice a day) improved symptoms of pain and
physical function during the short intervention without major adverse
events,” they admit that long-term effects on pain relief “could not be
confirmed” but should be investigated.
MSM Provides Arthritis Relief
Good news for people who suffer from muscle and joint pain, interstitial
cystitis, scleroderma, or allergies: Methylsulfonyl-methane, or MSM, is a
nutrient effective in alleviating the numerous debilitating symptoms caused
by each of these ailments. MSM is an extraordinary new dietary supplement
that is amazing users and researches alike because of its remarkable
benefits. Completely natural, MSM has vitamin-like effects that promote
normal growth and repair damaged mechanisms in the body.
MSM is extremely important to human beings because it provides a unique
dietary source of sulfur that we must have in order to function. MSM is a
special biological sulfur, 34% sulfur by weight, found in all plants,
soils, fruits, vegetables, and meats. According to Dr. Stanley W. Jacobs,
M.D., from the Oregon Health Sciences University in Portland, "MSM provides
a good portion of the body's need for sulfur. Sulfur is an important
building block." In fact, Dr. Jacob's comment might be an understatement.
Sulfur, one of the most abundant minerals in the body, is a component of
amino acids, vitamins, hormones, coenzymes, and antioxidants. Because
sulfur is necessary to build "disulfide bonds", it forms part of the body's
physical structure, including protein, collagen, glucosamine, skin, and
One of the strongest effects of MSM is its ability to relieve muscle pain
through the reduction of inflammation. People who suffer from sore joints
or arthritis benefit greatly from MSM because many of the components of
joints are made from collagen and glucosamine, which are both
sulfur-dependent. People with arthritis report substantial and long-lasting
relief while supplementing MSM in their diet in daily amounts ranging from
100 to 5,000 mg The beneficial effect is due in part to the ability of MSM
to sustain cell flow-through, allowing harmful substances to flow out while
permitting nutrients to flow in, and thereby preventing pressure buildup in
cells that cause inflammation in the joints and elsewhere, and translates
to pain. MSM, by equalizing cell pressure, treats the cause of
inflammation, unlike an aspirin that would treat the symptom by shutting
off the nerve.
The sulfuric content of MSM is also effective in combating various other
health problems. The anti-inflammation effect of the nutrient relieves the
painful bladder irritation of interstitial cystitis. MSM often works in
easing the symptoms of scleroderma and allergies as well. MSM is an
effective tool for preventing the everyday aches and pains common in people
who suffer from arthritis and from symptoms that can become debilitating if
left untreated. Jacobs calls it "... an important nutritional supplement.
MSM is safe and useful." More ailments eased by MSM include
gastrointestinal problems, acid stomach, and lung problems.
Because it is needed to form crucial blood proteins and amino acids, the
sulfur in MSM is essential to everyday living. Without proper levels of
MSM, our bodies are unable to build good, healthy cells, making them prone
to illness. When there is sufficient MSM in your system, your cells become
more permeable, enabling your body to quickly flush out any undesirable
foreign particles. If your body is sulfur deficient, the cell walls become
hard and stiff, hindering the flow of fluid through the cell walls.
LifeSource Vitamins - MSM 1,000 mg - May replace expensive drugs/nutrients
to treat arthritis, gastric hyperacidity, allergies, Shown to help remove
excess mercury from the body also reported helping maintain the health of
skin, hair, nails.
Here are some of the symptoms of MSM deficiency
1. Arthritis Conditions
2. Damage of the skin
4. Scar tissue
7. Sore muscles
9. Candida Infections 9 (albacans)
11. High Cholesterol
14. Joint, back, dental pain
15. Systemic inflammation
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