White Willow Bark Liquid Extract — 500 mg, Liquid, 1 fl oz — Supports Natural Pain Relief Headaches are brutal, thsese may help*
LifeSource Vitamins White Willow Bark Liquid Extract is a concentrated, ethically wild-harvested extract of Salix alba, traditionally used for pain and healthy inflammatory balance. Each 1 mL serving delivers the equivalent of 500 mg herb (1:2 extract) featuring naturally occurring salicin and polyphenols. Small, easy droppers make on-the-go use simple. Produced in FDA-registered, GMP-certified facilities and 3rd-party tested for identity, potency & purity.*
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Research Promise: At Lifesource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from 39 leading health organizations and insights from 20 top global universities to ensure our guidance aligns with credible science.*
Clinically Studied Benefits (with research)
• Helps relieve low back pain — Randomized, double-blind, placebo-controlled trial: standardized willow bark extract reduced pain intensity versus placebo in adults with acute exacerbations of chronic low back pain. (NIH/PubMed — Am J Med 2000)
• Comparable to an NSAID in RCT — Head-to-head study found willow bark extract provided clinically relevant pain relief comparable to rofecoxib in flare-ups of low back pain. (NIH/PubMed — Rheumatology 2001)
• Evidence synthesis supports analgesic effects — Meta-analysis and systematic reviews report benefit for low back pain with standardized extracts (dose-response signal with higher salicin content). (NIH/PubMed — 2004 meta-analysis; PMC — 2006 review)
• Osteoarthritis: mixed but promising — Early double-blind trials suggested reduced OA pain with standardized willow bark; later trials were neutral, indicating variability by preparation and dose. (NIH/PubMed — Phytother Res 2001; NIH/PubMed — 2014 RCT (neutral))
• Human-relevant anti-inflammatory action — Clinical and translational reviews detail willow’s salicin-derived salicylates and polyphenols supporting COX-pathway modulation and analgesia. (PMC — 2024 narrative review)
Additional Studies Showing Promising Benefits*
• Chronic low back pain (dose-response) — Earlier RCT reported greater responder rates at higher salicin doses (e.g., ~240 mg/day). (NIH/PubMed — 1998 RCT)
• Antioxidant/anti-inflammatory signaling — Willow bark preparations increased antioxidant enzymes and reduced inflammatory mediators in human-relevant models (supportive to pain pathways). (PMC — 2012 translational study)
• Traditional antipyretic use — Long history for fever and general aches; modern human trials focus more on musculoskeletal pain. (Context in NCCIH)
University Studies (Promising — Human / Academic Research)
• Clinical herbs for low back pain — Academic review summarizes RCTs of willow bark showing benefit in select formulations/doses for acute exacerbations. (PMC — 2006 university review)
• Pharmacology of salicin — University-led analyses chart absorption → salicylic acid conversion and factors that influence response and tolerance. (NIH/PubMed — pharmacokinetics overview)
Global Evidence & Authoritative Reviews*
• NCCIH — Evidence snapshot on uses, safety (salicylate sensitivity, anticoagulants), and traditional context for white willow bark. (NCCIH)
• MSKCC (About Herbs) — Clinical cautions (bleeding risk, pregnancy, interactions) and summary of trial evidence. (MSKCC)
We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge University, Oxford, Stanford, Yale, MIT, the University of Florida, Oregon State University – Linus Pauling Institute, Tufts, Boston University, Cornell, Columbia, and Ohio State — to ensure our guidance remains aligned with the highest standards of credible science.*
Brief Benefit Bullets
• Supports relief of low back discomfort*
• Helps maintain healthy inflammatory balance*
• Traditionally used for general aches & occasional fever*
• Easy liquid drops for fast, flexible dosing*
• 3rd-party lab tested for identity, potency & purity
Suggested Use
Add 1–2 droppers (~1 mL) to water/juice or take under the tongue, 1–2× daily, or as directed by your healthcare provider.* Do not use if allergic to salicylates/aspirin, if pregnant/nursing, in children/teens with viral illness, before surgery, or with anticoagulants/antiplatelets unless advised by your clinician. If you take other medicines, consult your physician.*
Product Specifications
• Serving Size — 1 mL (≈30 drops)
• Servings Per Container — ~30
• Herb Strength Ratio — 1:2 (500 mg herb weight equivalence per 1 mL)
• Ingredient — Ethically Wild-Harvested White Willow Bark (Salix alba)
• Other Ingredients — Grain alcohol (45–55% v/v), deionized water
• Form — Liquid extract (tincture)
• Free From — Non-GMO; gluten-free; soy-free*
• Quality — Third-party tested
Perfect For
• Adults seeking plant-based support for occasional musculoskeletal discomfort*
• Those preferring a liquid format for flexible dosing*
• Individuals looking for traditional salicin-containing botanicals*
Key Ingredients
White Willow Bark (Salix alba) — Source of salicin that converts to salicylic acid; RCTs/meta-analyses support benefit for low back pain in standardized preparations. (NIH/PubMed — Am J Med 2000; NIH/PubMed — 2004 meta-analysis)
Polyphenols (e.g., flavonoids) — Contribute antioxidant/anti-inflammatory activity; supportive translational evidence. (PMC — 2012)
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
White Willow Bark Liquid — traditional salicin support for occasional aches & low back comfort. Clinically Studied — NIH/PubMed!*
