LifeSource Vitamins Magtein® Magnesium L-Threonate — 2,000 mg — 90 Vegan Capsules — Supports Cognitive Function & Sleep Quality
LifeSource Vitamins Magtein® Magnesium L-Threonate provides magnesium in the patented Magtein® form, designed to support brain health and sleep quality. This supplement offers essential support for cognitive function and sleep quality, backed by studies in adults. Produced in FDA-registered, GMP-certified facilities, it is Non-GMO and free of wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts, and sesame.*
Research-Driven & Verified Product.
Explore the clinical research, ingredient science, and global evidence supporting this product below.
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. We also reference reviews from 39 leading health organizations and insights from 20 top global universities to keep our guidance aligned with credible, evidence-based science.* Every claim is supported by peer-reviewed human RCTs or meta-analyses whenever available.
Clinically Studied Benefits
✓ Supports cognitive function in older adults with cognitive complaints — 12-week randomized, double-blind, placebo-controlled trial of magnesium L-threonate (MMFS-01) reported cognitive score improvements vs. placebo.
NIH/PubMed — Liu, 2016
✓ Supports sleep quality & daytime functioning — Randomized controlled trial in adults with self-reported sleep problems found improved sleep quality (including deep/REM metrics) and daytime functioning with magnesium L-threonate vs. placebo.
NIH/PubMed — Pouteau, 2024
✓ Supports cognitive function in healthy adults — Double-blind, placebo-controlled study of Magtein®-based formula showed significant improvements in memory and cognition.
NIH/PubMed — Makkar, 2022
✓ Supports sleep efficiency in older adults with insomnia — Supplementation increased sleep time and efficiency in elderly with primary insomnia (RCT).
NIH/PubMed — Abbasi, 2012
✓ Supports blood pressure management already within normal range — Meta-analysis shows reductions in systolic and diastolic blood pressure with magnesium supplementation (meta-analysis of RCTs).
NIH/PubMed — Zhang, 2016
✓ Supports glucose metabolism — Improved fasting glucose and insulin sensitivity in at-risk individuals with magnesium (meta-analysis).
NIH/PubMed — Veronese, 2021
✓ Supports mood balance — Significant decline in depression scores in adults with depressive disorder with magnesium (meta-analysis).
NIH/PubMed — Dibaba, 2023
✓ Supports inflammation reduction — Decreased serum C-reactive protein levels in adults with magnesium (meta-analysis).
NIH/PubMed — Mazidi, 2018
✓ Supports metabolic health — Inverse association with risk of metabolic syndrome with higher magnesium intake (review/meta-analysis).
NIH/PubMed — Kim, 2025
✓ Supports oxidative stress reduction — Beneficial effects on biomarkers of oxidative stress and inflammation with magnesium (meta-analysis).
NIH/PubMed — Cepeda, 2025
✓ Supports sleep efficiency — Supplementation increased sleep time and efficiency in elderly with insomnia (RCT).
NIH/PubMed — Mah, 2021
✓ Supports migraine prevention — Reduced intensity and frequency of migraines with magnesium supplementation (meta-analysis).
NIH/PubMed — Chiu, 2016
Additional / Promising Evidence
✓ May support stress balance — Improved anxiety/depression scores in stressed adults with magnesium (review/RCT).
NIH/PubMed — Noah, 2021
✓ May enhance muscle function — Aids contraction and relaxation in preliminary studies (review).
NIH/PubMed — Tarsitano, 2024
✓ May support PMS symptoms — Relief of premenstrual mood changes with magnesium (RCT).
NIH/PubMed — Facchinetti, 1991
✓ May improve digestive regularity — Improved bowel movement frequency and transit time with magnesium (review).
NIH/PubMed — Mori, 2019
✓ May support exercise recovery — Reduced muscle soreness and improved performance after supplementation (review/RCT).
NIH/PubMed — Reno, 2022
✓ May support energy metabolism — Role in ATP pathways from mechanistic and human studies.
NIH/PubMed — Fatima, 2024
✓ May support athletic performance — Repletion supports electrolyte balance and function in athletes (review).
NIH/PubMed — Nielsen, 2006
✓ May support hormone balance — Improved sleep efficiency and hormone balance with magnesium (RCT).
NIH/PubMed — Carlos, 2024
University-Led & Academic Studies
✓ Massachusetts Institute of Technology (MIT) — Research on magnesium’s role in synaptic plasticity and cognitive health.
NIH/PubMed — Various, Ongoing
✓ Stanford University — Studies on magnesium L-threonate for brain magnesium levels and memory.
NIH/PubMed — Various, Ongoing
✓ Harvard Medical School — Insights on magnesium supplementation for sleep and mood.
NIH/PubMed — Various, Ongoing
✓ Oregon State University – Linus Pauling Institute — Reviews on magnesium’s metabolic and bone health benefits.
NIH/ODS — Linus Pauling Institute, Various
Global Evidence & Reviews
✓ NIH Office of Dietary Supplements — Magnesium fact sheet summarizing evidence for cognitive function, sleep, and brain health.
NIH/ODS — Magnesium Health Professional Fact Sheet
✓ National Center for Complementary and Integrative Health (NCCIH) — Reviews on magnesium for stress, sleep, and cognitive support.
NCCIH — Magnesium Overview
✓ Linus Pauling Institute — Comprehensive micronutrient information on magnesium L-threonate bioavailability and brain health.
LPI — Magnesium
We monitor research from leading institutions —
Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge, Oxford, Stanford, Yale, Tufts, University of Florida, Oregon State University – Linus Pauling Institute, Columbia, Cornell, Ohio State — to align with credible science.*
Key Ingredients
- Magtein® Magnesium L-Threonate (2,000 mg) — Patented form supporting cognitive function and sleep quality.
NIH/PubMed — Liu, 2016
Brief Benefit Bullets
- Supports cognitive function in older adults*
- Supports sleep quality & daytime functioning*
- Supports working memory & attention*
- Supports muscle & nerve function*
- Supports blood pressure management already within normal range*
- Supports migraine prevention*
Suggested Use
Take 3 capsules daily (may divide AM/PM), preferably with food, or as directed by your healthcare provider. Best results typically observed after ~30 days of continuous use. If pregnant, nursing, on medications, or have a medical condition, consult your physician.*
Product Specifications
- Serving Size: 3 Vegan Capsules (2,000 mg Magtein®) | Servings Per Container: 30
- Form: Vegan Capsules
- Free From: Non-GMO, free of wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts, sesame*
- Other Ingredients: Hypromellose (cellulose capsule), rice flour, stearic acid (vegetable source), silicon dioxide
- Made in FDA-Registered, GMP-Certified U.S. Facility
LifeSource Vitamins — Proudly American — Since 1992
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before taking any supplements.
Magtein® Magnesium L-Threonate 2000mg crosses blood-brain barrier for cognitive function, memory enhancement, sleep quality, and brain health. 3rd Party Tested & Backed by PubMed and NIH studies!*
