Vitamin E Effective Treatment for Abnormal Movement Disorder
Healthnotes Newswire (March 11, 2004)-People with schizophrenia or related mental disorder who develop involuntary movements of the arms, legs, or mouth (called tardive dyskinesia [TD]) after taking anti-psychotic medications may experience a reduction in these movements by taking supplemental vitamin E, reports the Journal of Clinical Psychopharmacology (2004;24:83-6). This is encouraging news for the millions of people around the world who suffer from this condition.
People with TD suffer from repetitive and uncontrollable movements-puckering of the lips or mouth, writhing of the arms or legs-that can interfere greatly with their quality of life. TD is most often associated with long-term use of anti-psychotic medications, such as chlorpromazine (Thoraziner), thioridazine (Mellarilr), or trifluoperazine (Stelaziner). It is believed that these medications increase free radicals in the body, which in turn injure the neurological system. Vitamin E is a potent antioxidant and may help protect the body against free-radical damage.
In the new study, 41 Chinese adults with schizophrenia between the ages of 30 and 60 years were randomly assigned to receive 1,200 IU per day of vitamin E or placebo for 12 weeks. The degree of TD was measured using the Abnormal Involuntary Movement Scale (AIMS) initially and after 6 and 12 weeks of treatment. Blood levels of superoxide dismutase (SOD), a critical enzyme involved with elimination of free radicals, were measured before and after treatment. People with TD have been shown to have lower levels of SOD than those without TD.
The degree of TD decreased by 46% in those taking vitamin E, compared with only 4% in those taking placebo. SOD levels increased by 30% in the vitamin E treatment group, while no significant increase in SOD was observed in the placebo group. In addition to the reduction of TD with vitamin E treatment, these findings suggest vitamin E also boosts SOD levels in the blood, which may offer additional protection against free-radical damage.
Studies suggest that other nutrients may be useful in treating TD. Choline, lecithin, and evening primrose oil may reduce the severity of TD, although large amounts are often necessary to achieve desirable results. One group of researchers treated approximately 11,000 schizophrenics with a mega-vitamin regimen that included vitamin C (up to 4 grams per day); vitamin B3, either as niacin or niacinamide (up to 4 grams per day); vitamin B6 (up to 800 mg per day); and vitamin E (up to 1,200 IU per day). During that time, not a single new case of TD was seen, even though many of the people were taking anti-psychotic drugs. Further research is needed to determine which nutrients or combinations of nutrients were most important for preventing TD. The amounts of niacinamide and vitamin B6 used in this research may cause significant side effects and should only be taken under the supervision of a physician.
Click here to see Vitamin
E supplements and more info at LifeSource Vitamins
E-mail Us: info@LifesourceVitamins.com
Call Us: 800.567.8122
We Are Built on Compassion - Driven by Faith & Powered by
Questions? It can be overwhelming we know. Call us, we will walk you through what
supplements will help you and which ones you really don’t need. It’s
what we do!
*Disclaimer: None of the above statements
have been evaluated by the FDA. These products are not intended to diagnose,
treat, cure or prevent any disease. As always, consult your physician before
taking any and all supplements. LifeSource Vitamins. Individual results may
Disclaimer: All the
information contained throughout this website is based upon the opinion of the
founder of LifeSource Vitamins, Bruce Brightman, and the entire team at
LifeSource Vitamins whose relentless research and studies have been ongoing on
since 1992. Other articles and
information are based on the opinions of the authors, who retains the copyright
as marked on the article. The
information on this site is not intended to replace your health care
professional, but to enhance your relationship with them. Doing your own studying and research and
taking your health care into your own hands is always best, especially in
partnership with your health care professional.
If you are pregnant, nursing, taking medications, or have any medical
conditions, always consult your health care professional before taking
supplements based on the information on this site.