Glucosamine & Chondroitin Plus MSM and Devil's Claw caps provide
important nutritional support for healthy joints and connective tissue.
Both compounds are major structural components found naturally in the body
that promote optimal joint connective tissue health. This unique formula
combines Glucosamine, Chondrotin, MSM, and Devil’s Claw to provide fast and
effective pain relief, while simultaneously nourishing cartilage,
ligaments, and tendons, and enhancing joint lubrication flexibility, and
mobility. It can be used to provide relief for conditions such as
arthritis, osteoarthritis, and physical overuse or as a preventative to
help maintain healthy joints and connective tissue.
is an amino sugar, consisting of an amino acid (glutamine) and a simple
sugar (glucose), that the body uses as the structural basis for connective
tissue and lubricating fluids. Amino sugars are the building blocks for
molecules called glycosaminoglycans (GAGs), which are large molecules that
form the glue-like matrix that holds the body together. While the body uses
approximately 20 different amino sugars, the GAG’s produced by glucosamine
specifically are used to make cartilage, ligaments, tendons, and bones.
Because connective tissue is constantly being broken down by normal
everyday use, the body requires a continuous supply of glucosamine to
replace or restructure the broken-down tissue. Severe stress, major
injuries, and aging osteoarthritis are associated with low GAG production.
In osteoarthritis, cartilage begins to thin and break down causing
stiffness, friction, and joint pain. Research indicates that
supplementation with glucosamine sulfate may help the body make more GAG’s,
increasing the amount of cartilage and fluid around the joints, helping
prevent further breakdown. A clinical trial comparing the use of
glucosamine sulfate and ibuprofen for pain relief in patients with TMJ
osteoarthritis reported that glucosamine provided greater relief from pain
caused by function during daily activities.
, found naturally in the body, is a major component of cartilage where it
helps absorb fluid into the connective tissue, provides the building blocks
for cartilage production, and may help prevent cartilage break down. In
osteoarthritis research, Chondroitin has been shown to reduce joint pain,
swelling, and stiffness and improve joint function. A double-blind,
placebo-controlled study evaluating the symptomatic effects of chondroitin
sulfate showed a significant increase in had function and decrease in pain
and morning stiffness compared to placebo. Studies evaluating the effects
of glucosamine and chondroitin combination therapy showed mixed results.
However, one of the largest studies, the 2008 Glucosamine/Chondroitin
Arthritis Intervention Trial (GAIT), reported that glucosamine combined
with chondroitin provided statistically significant pain relief compared to
placebo in patients experiencing moderate to severe pain.
(Methylsulphonylmethane). A metabolite of DMSO is a naturally occurring
sulfur compound found in humans that is anti-inflammatory, analgesic, and
protects cells against oxidative damage. It helps reduce joint pain,
improve joint movement, and prevent muscle damage. A clinical trial
evaluating the effects of MSM on patients with osteoarthritis reported that
MSM supplementation reduced pain and improved physical function compared to
placebo. Another study comparing the efficacy of glucosamine, MSM and their
combination on pain relief in knee osteoarthritis found that combination
therapy reduced swelling and provided greater pain relief and improved
joint function than individual therapy.
, a tuber from Africa contains harpagosides, glycosides that reduce
inflammation in the joints. It is used to alleviate arthritic and overuse
symptoms and is effective for both chronic and acute joint pain. It acts as
an analgesic in joints and seems to calm down inflammatory conditions in
the connective tissue. It can also help reduce chronic muscle pain, such as
is found in fibromyalgia. Also used for "hardening of the arteries"
(atherosclerosis), gout, muscle pain, back pain, fibromyalgia, tendonitis,
chest pain, gastrointestinal (GI) upset or heartburn, fever, and migraine
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as well as all Good Manufacturing Practices enforced by the FDA. CGMP's
provide for systems that assure proper design, monitoring, and control of
manufacturing processes and facilities. (
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