an amino sugar derived from the chitin of shellfish and is used by the body to
support healthy joint structures. Chondroitin
complements Glucosamine and works
synergistically to provide optimal nutritional support.*
There is no current recommended daily dosage
for glucosamine, however most people do best when taking 500 milligrams to
1500 milligrams daily, whether alone or in combination with other supplements
(like Chondroitin, Omega-3s or MSM supplements). Studies show the 500 to 1,500 dosage
lower inflammation and
help reverse autoimmune reactions
preserve joint health
reduce joint pain and
protect and repair gut
fight irritation to
the stomach, bladder and intestines
bowel disease and leaky gut syndrome
rebuild tissue and
stronger bones following fractures or injuries
What are Glucosamine and Chondroitin Sulfate?
Glucosamine and chondroitin sulfate are substances found naturally in the body. Glucosamine is a form of amino sugar that is believed to play a role in cartilage formation and repair. Chondroitin sulfate is part of a large protein molecule (proteoglycans) that gives cartilage elasticity.*
Both glucosamine and chondroitin sulfate are sold as dietary or nutritional supplements. They are extracted from animal tissue: glucosamine from crab, lobster or shrimp shells; and chondroitin sulfate from animal cartilage, such as tracheas or shark cartilage.*
What do they do?
Past studies show that some people with mild to moderate osteoarthritis (OA) taking either glucosamine or chondroitin sulfate reported pain relief at a level similar to that of nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen. Some research indicates that the supplements might also slow cartilage damage in people with OA. Definitive results about the effects of these supplements are expected from an in-depth clinical study currently being conducted by the National Institutes of Health.*
What do I look for?
Because dietary supplements are unregulated, the quality and content may vary widely. If you decide to take these supplements:
• Choose products sold by large, well-established companies that can be held accountable.
• Read the product labels carefully to make sure the ingredient lists make sense to you. If you have trouble, ask your pharmacists for help.
• Be sure to consult your doctor before deciding to try these supplements.
• Make sure that OA is the cause of your pain.
• Do not stop or reduce your current prescribed medications without talking with your doctor.
How do I take them?
If you decide to take these supplements, consult your doctor about the proper dosage. The amount used in studies of glucosamine was 1,500 mg per day and in studies of chondroitin sulfate, 1,200 mg per day was used. You can try the supplements along with your current medications for six to eight weeks. If you don't experience any difference in your symptoms within a few months, you probably will not get any relief from using the supplements.*
Are there side effects?
The most common side effects are increased intestinal gas and softened stools. If you experience these problems, you might want to try another supplement brand before you stop using them altogether. More studies need to be done to confirm the safety and effectiveness of the supplements. Be sure to contact your doctor if you notice any unusual or new symptoms while you are taking them.
• Children, women who are pregnant, and women who could become pregnant should not take these supplements. They have not been studied long enough to determine their effects on a child or on a developing fetus.
• Because glucosamine is an amino sugar, people with diabetes should check their blood sugar levels more frequently when taking this supplement.
• If you are taking chondroitin sulfate in addition to a blood-thinning medication or daily aspirin therapy, have your blood clotting time checked more often. This supplement is similar in structure to the blood-thinning drug heparin, and the combination may cause bleeding in some people.
• If you are allergic to shellfish, consult your doctor before deciding to take glucosamine. In most cases, however, allergies are caused by proteins in shellfish, not chitin, a carbohydrate from which glucosamine is extracted.
British Research study finds:
Objective: The purpose of this
study was to examine the effects of oral glucosamine supplementation on the
functional ability and degree of pain felt by individuals who had regular knee
pain, most likely due to previous articular cartilage damage, and possibly
Methods: Subjects were
randomly supplemented with either glucosamine (G) (n=24) or placebo (P)
(lactose) (n=22) for 12 weeks at a dose of 1000 mg per day. Over this period,
four testing sessions were conducted, with changes in knee pain and function
assessed by clinical and functional tests, (joint line palpation, a 3 meter "duck
walk" and a repeated, walking stair climb), two questionnaires (the Knee
Injury and Osteoarthritis Outcome Score (KOOS) and the Knee Pain Scale (KPS))
and participant subjective evaluations.
Results: The clinical and
functional test scores improved with time (main effects: p<0.05, p<0.01)
but there were no significant differences between the two groups. The
questionnaire results also recorded a significant main effect for time
(p<0.05), but the glucosamine group was found to have significantly better
KOOS quality of life scores at week eight and 12 (p<0.05), and lower KPS
scores (p<0.05) at week eight than the placebo group. On self-report
evaluations of changes across the 12 week supplementation period, 88% (n=21) of
the glucosamine group reported some degree of improvement in their knee pain
versus only 17% (n=3) in the placebo group.
These results suggest that glucosamine supplementation can provide some degree
of pain relief and improved function in persons who experience regular knee pain,
which may be caused by prior cartilage injury and/or osteoarthritis. The trends
in the results also suggest that, at a dosage of 1,000 mg per day, the majority
of improvements are present after eight weeks.
Vitamins - Glucosamine 1,500mg & Chondroitin 1,200mg Glucosamine is used by
the body to support healthy joint structures. Chondroitin compliments
Glucosamine and works synergistically to provide optimal joint & arthritis
Have Questions on this
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*Disclaimer: None of the above
statements have been evaluated by the FDA. These products are not intended to
diagnose, treat, cure or prevent any disease. As always, consult your physician
before taking any and all supplements. LifeSource Vitamins. Individual results
Disclaimer: All the
information contained throughout this website is based upon the opinion of the
founder of LifeSource Vitamins, Bruce Brightman, and the entire team at
LifeSource Vitamins whose relentless research and studies have been ongoing
since 1992. Other articles and information are based on the opinions of
the authors, who retain the copyright as marked on the article. The
information on this site is not intended to replace your health care
professional, but to enhance your relationship with them. Doing your own
studying and research and taking your health care into your own hands is always
best, especially in partnership with your health care professional. If you
are pregnant, nursing, taking medications, or have any medical conditions,
always consult your health care professional before taking supplements based on
the information on this site.