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Lifesource Vitamins Betaine HCl + Pepsin — Targeted Digestive Support*
This formula pairs Betaine Hydrochloride (HCl) with an acid-stable fungal protease (“fungal pepsin” from Aspergillus niger) to support healthy gastric acidity and efficient protein digestion at mealtime.* Produced in GMP facilities and third-party tested for identity, potency, and purity.*
Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from 39 leading health organizations and insights from 20 top global universities to ensure our guidance aligns with credible science.*
• Rapid gastric re-acidification* — Single doses of betaine HCl quickly lowered elevated gastric pH in volunteers with induced hypochlorhydria. (NIH/PMC — Heidelbaugh J, 2013)
• Improved exposure of pH-dependent compounds* — Re-acidifying the stomach with betaine HCl increased exposure of a weakly basic drug with pH-dependent solubility. (NIH/PMC — Williams J, 2014)
• Meal-time use investigated* — Human work evaluated BHCl during fed conditions and effects on post-meal gastric pH. (NIH/PubMed — Derakhshan M, 2020)
• Protein digestion support* — Acid-stable proteases from Aspergillus niger (An-PEP/aspergillopepsins) actively digest dietary proteins in gastric pH; human studies show enhanced gluten protein breakdown. (NIH/PMC — Tack J, 2015; NIH/PMC — König J, 2024)
• Acid-stable by design* — A. niger aspartic proteases are active and stable under acidic gastric conditions (biochemical/structural work). (NIH/PubMed — Bhattacharya S, 2019; NIH/PMC — Kanerva A, 2020)
• Practical dosing context* — Reviews outline fed/fasted timing and considerations for BHCl use. (NIH/PMC — Hwang C, 2016; NIH/PubMed — Derakhshan M, 2020)
• Case-level evidence* — BHCl + pepsin use before protein meals improved symptoms and weight in an individual case. (NIH/PubMed — Kim H, 2024)
• Gut barrier & microbiome (emerging)* — Betaine supported intestinal morphology and microbiota in stress models. (NIH/PMC — Wu Q, 2018; NIH/PMC — Zhang Y, 2023)
• Enzyme characterization* — Academic work on A. niger protease kinetics and substrate handling. (NIH/PubMed — Bhattacharya S, 2019)
• Digestive physiology context* — University-led reviews describe gastric pH dynamics and nutrient absorption challenges. (NIH/PMC — Hwang C, 2016)
• NIH Office of Dietary Supplements — Fact sheet on dietary supplements and digestive aids (stable URL). (NIH/ODS — 2024)
• NCCIH — Complementary digestive support research overview. (NCCIH — 2024)
• Supports healthy stomach acidity for digestion*
• Helps break down dietary proteins with acid-stable protease*
• Backs nutrient absorption for pH-sensitive compounds*
• Designed for mealtime digestive support*
3rd-party lab tested for identity, potency & purity
See product label for full instructions, or as directed by your healthcare professional. Do not exceed recommended dose. If pregnant, nursing, taking medications, or have a medical condition, consult your physician.*
• Serving Size — 2 Veg Capsules
• Servings Per Container — 60
• Betaine HCl — 1,296 mg**
• Acid-Stable Protease (300 SAPU, Fungal Pepsin from Aspergillus niger) — 300 mg**
• Form — Easy-to-swallow vegetarian capsules
• Free From — Non-GMO, gluten-free; not manufactured with yeast, soy, milk, egg, fish, shellfish, tree nuts, or sesame
• Quality — Third-party tested for identity, potency & purity
• Note — Natural color variation may occur
3rd-Party Testing: Every batch is verified by independent labs for identity, potency, and purity. Click here to see our 3rd-party testing.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Betaine HCl + Pepsin — digestive support for protein breakdown, nutrient absorption & gastric pH balance. Clinically Studied Ingredients — NIH/PubMed!*

*Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before taking any supplements. Individual results may vary. This information is not intended to replace your healthcare provider but to support and enhance that relationship. You are encouraged to do your own research and take an active role in your health decisions. If you are pregnant, nursing, taking medications, or have any medical conditions, consult your healthcare professional before using any supplements discussed on this site.