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25% off Immune Support Products Code: IMMUNE25

Betaine HCI - 1,296 mg (Betaine Hydrochloride) w/ Protease  - 120 Veg Capsules
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Betaine HCI - 1,296 mg (Betaine Hydrochloride) w/ Protease - 120 Veg Capsules

LifeSource Vitamins
5 Reviews
$
  • Promotes digestive health with betaine HCl*
  • Supports heartburn relief and nutrient absorption*
  • Enhances protein metabolism and B12 uptake*
  • Helps reduce bloating and gas*
  • Supports liver and cardiovascular health*
  • Promotes immune function via nutrient support*
  • Rapidly supports healthy gastric pH*
  • 3rd-party lab tested for purity & potency
Product Code: BETA005

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Lifesource Vitamins Betaine HCl + Pepsin — Targeted Digestive Support*

This formula pairs Betaine Hydrochloride (HCl) with an acid-stable fungal protease (“fungal pepsin” from Aspergillus niger) to support healthy gastric acidity and efficient protein digestion at mealtime.* Produced in GMP facilities and third-party tested for identity, potency, and purity.*

Research Promise: At LifeSource Vitamins, our commitment is rooted in research and results. Every benefit below is supported by human clinical studies indexed in the National Institutes of Health (NIH) via PubMed, with full texts available in the National Library of Medicine (NLM) PubMed Central (PMC) when available. In addition, we reference reviews from 39 leading health organizations and insights from 20 top global universities to ensure our guidance aligns with credible science.*

Clinically Studied Benefits (with research)

Rapid gastric re-acidification* — Single doses of betaine HCl quickly lowered elevated gastric pH in volunteers with induced hypochlorhydria. (NIH/PMC — Heidelbaugh J, 2013)

Improved exposure of pH-dependent compounds* — Re-acidifying the stomach with betaine HCl increased exposure of a weakly basic drug with pH-dependent solubility. (NIH/PMC — Williams J, 2014)

Meal-time use investigated* — Human work evaluated BHCl during fed conditions and effects on post-meal gastric pH. (NIH/PubMed — Derakhshan M, 2020)

Protein digestion support* — Acid-stable proteases from Aspergillus niger (An-PEP/aspergillopepsins) actively digest dietary proteins in gastric pH; human studies show enhanced gluten protein breakdown. (NIH/PMC — Tack J, 2015; NIH/PMC — König J, 2024)

Additional Studies Showing Promising Benefits*

Acid-stable by design*A. niger aspartic proteases are active and stable under acidic gastric conditions (biochemical/structural work). (NIH/PubMed — Bhattacharya S, 2019; NIH/PMC — Kanerva A, 2020)

Practical dosing context* — Reviews outline fed/fasted timing and considerations for BHCl use. (NIH/PMC — Hwang C, 2016; NIH/PubMed — Derakhshan M, 2020)

Case-level evidence* — BHCl + pepsin use before protein meals improved symptoms and weight in an individual case. (NIH/PubMed — Kim H, 2024)

Gut barrier & microbiome (emerging)* — Betaine supported intestinal morphology and microbiota in stress models. (NIH/PMC — Wu Q, 2018; NIH/PMC — Zhang Y, 2023)

University / Academic Context*

Enzyme characterization* — Academic work on A. niger protease kinetics and substrate handling. (NIH/PubMed — Bhattacharya S, 2019)

Digestive physiology context* — University-led reviews describe gastric pH dynamics and nutrient absorption challenges. (NIH/PMC — Hwang C, 2016)

Global Evidence & Authoritative Reviews*

NIH Office of Dietary Supplements — Fact sheet on dietary supplements and digestive aids (stable URL). (NIH/ODS — 2024)

NCCIH — Complementary digestive support research overview. (NCCIH — 2024)

We monitor research from the world’s leading institutions — including Harvard, Johns Hopkins, Mayo Clinic, Cleveland Clinic, Cambridge University, Oxford, Stanford, Yale, MIT, the University of Florida, Oregon State University – Linus Pauling Institute, Tufts, Boston University, Cornell, Columbia, and Ohio State — to ensure our guidance remains aligned with credible science.*
Brief Benefit Bullets

• Supports healthy stomach acidity for digestion*

• Helps break down dietary proteins with acid-stable protease*

• Backs nutrient absorption for pH-sensitive compounds*

• Designed for mealtime digestive support*

3rd-party lab tested for identity, potency & purity

Suggested Use

See product label for full instructions, or as directed by your healthcare professional. Do not exceed recommended dose. If pregnant, nursing, taking medications, or have a medical condition, consult your physician.*

Product Specifications

Serving Size — 2 Veg Capsules
Servings Per Container — 60
Betaine HCl — 1,296 mg**
Acid-Stable Protease (300 SAPU, Fungal Pepsin from Aspergillus niger) — 300 mg**
Form — Easy-to-swallow vegetarian capsules
Free From — Non-GMO, gluten-free; not manufactured with yeast, soy, milk, egg, fish, shellfish, tree nuts, or sesame
QualityThird-party tested for identity, potency & purity
Note — Natural color variation may occur

3rd-Party Testing: Every batch is verified by independent labs for identity, potency, and purity. Click here to see our 3rd-party testing.

LifeSource Vitamins — Proudly American — Since 1992

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Betaine HCl + Pepsin — digestive support for protein breakdown, nutrient absorption & gastric pH balance. Clinically Studied Ingredients — NIH/PubMed!*



Betaine HCI - 1,296 mg (Betaine Hydrochloride) w/ Protease - 120 Veg Capsules

$21.99
  • Click Here to See our 3rd Party Testing On Every Single Nutrient and Every Product Sold at Lifesource Vitamins.

    *Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your physician before taking any supplements. Individual results may vary. This information is not intended to replace your healthcare provider but to support and enhance that relationship. You are encouraged to do your own research and take an active role in your health decisions. If you are pregnant, nursing, taking medications, or have any medical conditions, consult your healthcare professional before using any supplements discussed on this site.

Reviews

Average Rating:
( 5 )
Elen ***
August 20, 2025
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Tammy*** from Newcastle, United States
August 20, 2025
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richa*** from Taylor, United States
August 20, 2025
Wisdom
I take a capsule before i eat it helps with digestion i understand Acid reflux is because of not enough stomach Acid. I am pro active i don't have Acid reflux and don't want it. I ALSO have found chewing my food throughly and avoiding drinking my ice Tea till after i have eaten helps to keep a strong stomach Acid.
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Tammy*** from Newcastle, United States
April 14, 2025
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Elen *** from n/a
August 29, 2024
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