- Helps Depression and Moods
stands for S-adenosyl methionine, a naturally occurring molecule that is widely
used in Europe for depression. It is
found throughout the body. The liver,
adrenal glands, and brain have high concentrations of SAM-e.
Research offers hope to patients who haven’t
been helped by traditional antidepressant treatment. Studies suggest that for
more than half of depressed patients, antidepressants alone don’t eliminate
symptoms. That is why taking SAM-e
in addition to antidepressants show a marked improvement. SAM-e
should not be taken in combination with a prescription antidepressant without
the monitoring of a health professional. Other studies
have shown that using SAM-e alone can benefit many patients.
is an important methyl donor, an essential step in the synthesis of several
neurotransmitters from amino acids in the diet. The antidepressant effects
of SAM-e are probably related to multiple mechanisms of action including
increased brain levels of serotonin, dopamine, and norepinephrine.
The standard maintenance regimen of oral SAM-e
for depressed mood is between 800 and 1600 mg per day in two to four divided
doses. A common dosing strategy is to start SAM-e at a dose of 200 mg twice
daily, and gradually increase to 400 mg twice daily, monitoring for side
effects and therapeutic response. Absorption is improved when SAM-e is taken on
an empty stomach (i.e., before meals).
is a study:
See All LifeSource Vitamins SAM-e Products,
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Bruce Brightman – founder
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