What is 5-HTP?
Is LifeSource's Safe?
by Bruce Brightman - founder,
5-HTP is a metabolite (a substance produced by metabolism) of the amino
acid tryptophan. You may know tryptophan as the substance in turkey that
makes you feel like taking a nap after Thanksgiving dinner. 5-HTP is a
direct precursor of the important inhibitory neurotransmitter serotonin,
which is secreted in response to mood or emotion swings. Serotonin soothes
and calms and brings about feelings of contentment. It is also the
precursor to the antioxidant and sleep enhancer called melatonin, which is
produced in the pineal gland by the conversion of serotonin.
Is 5-HTP safe to take? The FDA has warned that it has found batches
with impurities similar to the Japanese batches of tryptophan in 1980.
5-HTP and tryptophan are not the same. 5-HTP is related to tryptophan, but
is derived from a different source. The 1980 scare concerning the Japanese
tryptophan was attributed to a large batch the Japanese produced that was
contaminated during the fermentation and/or filtration process. The
contaminant caused affected persons to develop symptoms of EMS
5-HTP, unlike tryptophan, is now extracted from the seed of the Griffonia
simplicifolia plant and is not produced via bacterial fermentation,
virtually eliminating further occurrence of EMS. The contaminant believed
to have caused the tryptophan contamination has not been identified as
being present in 5-HTP.
Does Lifesource check for Peak X contamination in the 5-HTP product?
Our 5-Hydroxytryptophan (5-HTP) is the highest quality >99% pure
material available. The culprit in the tryptophan problem some years ago
was supposedly due to a compound dubbed Peak X. Our 5-HTP is Peak X free.
We also require total Impurities [e.g. the synthetic D-form, determined by
HPLC] to be not more than 0.5%, Chloride less than 100 parts per million,
Tryptophan not more than 0.05%, and Serotonin has to be absent. Our website
is a great source for info on our quality efforts.
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Every LifeSource Vitamins product exceeds all regulatory standards and
requirements set forth in the FDA's Code of Federal Regulation. (
21 CFR, part 111
as well as all Good Manufacturing Practices enforced by the FDA. CGMP's
provide for systems that assure proper design, monitoring, and control of
manufacturing processes and facilities. (
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None of the above statements have been evaluated by the FDA. These products
are not intended to diagnose, treat, cure or prevent any disease.
As always, consult your physician before taking any and all
LifeSource Vitamins. Individual results may vary.
All the information contained throughout this website is based upon the
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entire team at LifeSource Vitamins whose relentless research and studies
have been ongoing since 1992. Other articles and information are based on
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